Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.41 |
| ▸ | WNT3A | P56704 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865396 | 0.82 | TSHR (0.43) | LMNACYP3A4TSHRKMT2ATDP1 | |
| SCHEMBL1405144 | 0.78 | LMNA (0.58) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL10519876 | 0.78 | LMNA (0.58) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL27570825 | 0.77 | LMNA (0.56) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL11074677 | 0.77 | LMNA (0.56) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL28254424 | 0.77 | TSHR (0.57) | LMNAGAAMAPTTSHRKMT2A | |
| SCHEMBL4027098 | 0.75 | ALDH1A1 (0.54) | GAACYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL513905 | 0.75 | LMNA (0.55) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL45490 | 0.75 | LMNA (0.59) | LMNAGAAMAPTTSHRKMT2A | |
| SCHEMBL28284599 | 0.75 | LMNA (0.55) | LMNAGAACTNNB1WNT3ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071519-A9 | OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |