Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493579 | 0.85 | RAB9A (0.49) | RAB9ANPC1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL8496474 | 0.80 | NPC1 (0.51) | RAB9ANPC1HTTKMT2ACYP1A2 | |
| SCHEMBL11542709 | 0.78 | KMT2A (0.39) | KMT2ANPSR1MAPT | |
| SCHEMBL8495371 | 0.78 | RAB9A (0.56) | RAB9ANPC1HTTATMKDM4E | |
| SCHEMBL8493684 | 0.78 | RAB9A (0.53) | RAB9ANPC1HTTATMKDM4E | |
| SCHEMBL8495127 | 0.78 | RAB9A (0.53) | RAB9ANPC1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6483915 | 0.74 | HSD11B1 (0.44) | RAB9ANPC1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL6482322 | 0.74 | LMNA (0.47) | RAB9ANPC1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL2767333 | 0.72 | TP53 (0.42) | RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1558713 | 0.70 | RAB9A (0.70) | RAB9ANPC1HTTATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999011621-A2 | THIOUREA FOR INCREASING HDL-CHOLESTEROL LEVELS, WHICH ARE USEFUL AS ANTI-ATHEROSCLEROTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-11 | — | — | WO | claimed |
| WO-1999011621-A2 | THIOUREA FOR INCREASING HDL-CHOLESTEROL LEVELS, WHICH ARE USEFUL AS ANTI-ATHEROSCLEROTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-11 | — | — | WO | disclosed |