Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495127 | 0.85 | RAB9A (0.53) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL8496103 | 0.85 | RAB9A (0.49) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL11542709 | 0.78 | KMT2A (0.39) | MAPTKMT2AGAANPSR1TP53 | |
| SCHEMBL8496474 | 0.78 | NPC1 (0.51) | RAB9ANPC1MEN1KMT2ALCK | |
| SCHEMBL8492114 | 0.78 | NPC1 (0.50) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL8491870 | 0.78 | NPC1 (0.53) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL2634981 | 0.75 | RAB9A (0.56) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL6483915 | 0.74 | HSD11B1 (0.44) | RAB9ANPC1KMT2ALCKSMN1; SMN2 | |
| SCHEMBL6482322 | 0.74 | LMNA (0.47) | RAB9ANPC1MAPTKMT2AGAA | |
| SCHEMBL27488058 | 0.71 | L3MBTL1 (0.64) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999011621-A2 | THIOUREA FOR INCREASING HDL-CHOLESTEROL LEVELS, WHICH ARE USEFUL AS ANTI-ATHEROSCLEROTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-11 | — | — | WO | disclosed |