Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | G6PC1 | P35575 | 5/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497605 | 1.00 | MAPT (0.63) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8498156 | 0.82 | G6PC1 (0.72) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8498157 | 0.82 | G6PC1 (0.72) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL9809671 | 0.81 | MAPT (0.79) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL9809673 | 0.81 | MAPT (0.79) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL130652 | 0.79 | ALDH1A1 (0.78) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL28045555 | 0.78 | MEN1 (0.49) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11238435 | 0.77 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11238432 | 0.77 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8499120 | 0.77 | MAPT (0.73) | MAPTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |