Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011152 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL5546357 | 0.80 | ATM (0.41) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9011089 | 0.73 | MEN1 (0.42) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL5684840 | 0.68 | HPGD (0.51) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL7042998 | 0.66 | MEN1 (0.48) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL5134000 | 0.66 | — | — | |
| SCHEMBL9010948 | 0.65 | MEN1 (0.40) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL16470550 | 0.63 | CYP1A2 (0.35) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL11004477 | 0.62 | ATM (0.48) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL17867480 | 0.61 | KMT2A (0.51) | KDM4EALDH1A1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985824-A | Methods and compositions for treating cystic fibrosis | GENZYME CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |