Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16204250 | 0.72 | ADRA2C (0.44) | MAPTALDH1A1TDP1KDM4EPOLB | |
| SCHEMBL31499299 | 0.69 | KMT2A (0.40) | ALDH1A1KMT2AHTR2ACHRM2CYP2D6 | |
| SCHEMBL1782470 | 0.69 | KMT2A (0.40) | ALDH1A1TDP1KDM4EKMT2AHTR2A | |
| SCHEMBL6651178 | 0.69 | KMT2A (0.40) | ALDH1A1TDP1KDM4EKMT2AHTR2A | |
| SCHEMBL24181427 | 0.69 | POLB (0.42) | MAPTALDH1A1TDP1KDM4EPOLB | |
| SCHEMBL8495606 | 0.67 | ALDH1A1 (0.48) | MAPTALDH1A1TDP1KDM4EPOLB | |
| SCHEMBL6244315 | 0.67 | L3MBTL1 (0.46) | MAPTALDH1A1TDP1KDM4EPOLB | |
| SCHEMBL8897003 | 0.67 | CETP (0.48) | MAPTALDH1A1TDP1KDM4EPOLB | |
| SCHEMBL98494 | 0.67 | KMT2A (0.39) | MAPTALDH1A1KDM4EHSD17B10L3MBTL1 | |
| SCHEMBL5503227 | 0.66 | KMT2A (0.38) | ALDH1A1TDP1L3MBTL1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903341-A1 | \"Novel ortho-mercaptoaniline compounds\ | Akzo Nobel N.V. (NL) | 1999-03-24 | — | — | EP | disclosed |