Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495606 | 0.84 | ALDH1A1 (0.48) | MAPTNPSR1KDM4EUSP2ALDH1A1 | |
| SCHEMBL6244315 | 0.84 | L3MBTL1 (0.46) | CETPMAPTNPSR1KDM4EUSP2 | |
| SCHEMBL12457090 | 0.81 | APOBEC3G (0.59) | CETPMAPTNPSR1KDM4EUSP2 | |
| SCHEMBL18684672 | 0.80 | POLB (0.43) | CETPMAPTNPSR1KDM4EUSP2 | |
| SCHEMBL24181427 | 0.77 | POLB (0.42) | CETPMAPTNPSR1KDM4EUSP2 | |
| SCHEMBL13374975 | 0.77 | TDP1 (0.53) | MAPTNPSR1KDM4EUSP2ALDH1A1 | |
| SCHEMBL16204250 | 0.77 | ADRA2C (0.44) | CETPMAPTNPSR1KDM4EUSP2 | |
| SCHEMBL14383870 | 0.77 | ADRA2A (0.46) | CETPMAPTNPSR1KDM4EUSP2 | |
| SCHEMBL29449705 | 0.76 | POLB (0.60) | MAPTNPSR1KDM4EUSP2ALDH1A1 | |
| SCHEMBL653948 | 0.76 | POLB (0.60) | MAPTNPSR1KDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643872-A | ANTIAGGLOMERANTS FOR PLATELETS, ANTICOAGULANTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0425212-A2 | Cyclic anti-aggregatory peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-02 | — | — | EP | disclosed |