Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499887 | 0.88 | CAPN1 (0.57) | CAPN1 | |
| SCHEMBL8499510 | 0.81 | CAPN1 (0.52) | CAPN1 | |
| SCHEMBL8499745 | 0.78 | CAPN1 (0.66) | CAPN1 | |
| SCHEMBL8498097 | 0.76 | CAPN1 (0.54) | CAPN1L3MBTL1 | |
| SCHEMBL8499658 | 0.71 | CAPN1 (0.53) | CAPN1CA1CA2L3MBTL1SMN1; SMN2 | |
| SCHEMBL8497491 | 0.70 | CAPN1 (0.53) | CAPN1SLC6A4 | |
| SCHEMBL7351908 | 0.69 | CAPN1 (0.68) | CAPN1 | |
| SCHEMBL8496327 | 0.69 | CAPN1 (0.59) | CAPN1 | |
| SCHEMBL7445124 | 0.68 | CA1 (0.49) | CA1CA2CYP2D6 | |
| SCHEMBL11718084 | 0.66 | MAOA (0.39) | CAPN1MAOAMAOBSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952328-A | MAY BE USED TO ALLEVIATE, MEDIATE, REDUCE AND/OR PREVENT DISORDERS WHICH ARE ASSOCIATED WITH ABNORMAL AND/OR ABERRANT ACTIVITY OF CYSTEINE PROTEASES AND/OR SERINE PROTEASES | CEPHALON, INC. (US) | 1999-09-14 | — | — | US | disclosed |