Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 5/20 | 0.66 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351908 | 0.91 | CAPN1 (0.68) | CAPN1BCHEAGTR2 | |
| SCHEMBL8498396 | 0.78 | CAPN1 (0.53) | CAPN1 | |
| SCHEMBL8499887 | 0.71 | CAPN1 (0.57) | CAPN1AGTR2 | |
| SCHEMBL27938420 | 0.68 | SIGMAR1 (0.47) | CAPN1BCHEAGTR2 | |
| SCHEMBL11147860 | 0.64 | SPHK1 (0.52) | — | |
| SCHEMBL29695296 | 0.64 | ACHE (0.63) | — | |
| SCHEMBL8499658 | 0.64 | CAPN1 (0.53) | CAPN1 | |
| SCHEMBL15903276 | 0.64 | BCHE (0.65) | BCHE | |
| SCHEMBL3051745 | 0.63 | REV1 (0.64) | BCHE | |
| Hydrochloric Acid SCHEMBL3238921 | 0.63 | BCHE (0.66) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952328-A | MAY BE USED TO ALLEVIATE, MEDIATE, REDUCE AND/OR PREVENT DISORDERS WHICH ARE ASSOCIATED WITH ABNORMAL AND/OR ABERRANT ACTIVITY OF CYSTEINE PROTEASES AND/OR SERINE PROTEASES | CEPHALON, INC. (US) | 1999-09-14 | — | — | US | disclosed |