Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 5/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | CCKAR | P32238 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861992 | 0.85 | ITGB3 (0.52) | SENP1ITGB1ITGB3ITGA2BITGAV | |
| SCHEMBL7864217 | 0.85 | ITGB3 (0.52) | SENP1ITGB1ITGB3ITGA2BITGAV | |
| SCHEMBL7856521 | 0.75 | PPARG (0.60) | SENP1ITGB1ITGB3ITGA2BITGAV | |
| SCHEMBL7377637 | 0.75 | MAPT (0.55) | SENP1ITGB3ITGA2BPPARG | |
| SCHEMBL7862001 | 0.74 | ITGB3 (0.48) | SENP1ITGB1ITGB3ITGA2BITGAV | |
| SCHEMBL7861998 | 0.74 | ITGB3 (0.48) | SENP1ITGB1ITGB3ITGA2BITGAV | |
| SCHEMBL7377320 | 0.74 | ITGB1 (0.70) | ITGB1ITGA4ITGB3ITGA2BITGAV | |
| SCHEMBL7377326 | 0.74 | ITGB1 (0.70) | ITGB1ITGA4ITGB3ITGA2BITGAV | |
| SCHEMBL7856474 | 0.73 | SIRT2 (0.51) | SENP1ALDH1A1L3MBTL1SIRT2PPARG | |
| SCHEMBL8497730 | 0.71 | SENP1 (0.48) | SENP1ITGB3ITGA2BITGAVPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1999-01-13 | — | — | EP | claimed |
| WO-1997036862-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |