Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527944 | 0.95 | MEN1 (0.55) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL11525183 | 0.88 | GAA (0.55) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL3389458 | 0.86 | KMT2A (0.57) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL11059841 | 0.84 | MEN1 (0.61) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL2820949 | 0.82 | ESR1 (0.61) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL5710076 | 0.82 | ESR1 (0.61) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL2822090 | 0.82 | ESR1 (0.61) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL12067867 | 0.80 | LMNA (0.54) | KMT2AMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL11673189 | 0.80 | ALDH1A1 (0.54) | MEN1KMT2ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL9412084 | 0.80 | MEN1 (0.48) | MEN1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11043474-A | — | — | None | — | — | JP | disclosed |
| JP-H1143474-A | PRODUCTION OF AMINOBENZENE COMPOUND | TAKEDA CHEM IND LTD | 1999-02-16 | — | — | JP | disclosed |