Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | CACNA1F | O60840 | 6/20 | 0.60 |
| ▸ | CACNA1D | Q01668 | 6/20 | 0.60 |
| ▸ | CACNA1S | Q13698 | 6/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710076 | 1.00 | ESR1 (0.61) | ESR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL2822090 | 1.00 | ESR1 (0.61) | ESR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3389458 | 0.95 | KMT2A (0.57) | ESR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3391506 | 0.89 | LMNA (0.61) | KMT2ATP53LMNAMEN1MAPT | |
| SCHEMBL11527944 | 0.87 | MEN1 (0.55) | ESR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3646790 | 0.86 | TP53 (0.56) | CACNA1FCACNA1DCACNA1SCACNA1CKMT2A | |
| SCHEMBL9169504 | 0.86 | ESR1 (0.71) | ESR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11700483 | 0.86 | ESR1 (0.71) | ESR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9164746 | 0.86 | ESR1 (0.71) | ESR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9678186 | 0.86 | ESR1 (0.71) | ESR1CACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2157159-B1 | HYDRAULIC FLUID | IDEMITSU KOSAN CO (JP) | 2015-12-02 | — | — | EP | disclosed |
| EP-2674473-A2 | Hydraulic fluid and hydraulic system | IDEMITSU KOSAN CO., LTD. (JP) | 2013-12-18 | — | — | EP | disclosed |
| US-8299004-B2 | Hydraulic fluid and hydraulic system | IDEMITSU KOSAN CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20100130394-A1 | HYDRAULIC FLUID AND HYDRAULIC SYSTEM | IDEMITSU KOSAN CO., LTD (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-2157159-A1 | HYDRAULIC FLUID AND HYDRAULIC SYSTEM | Idemitsu Kosan Co., Ltd. (JP) | 2010-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130394-A1 | HYDRAULIC FLUID AND HYDRAULIC SYSTEM | AQP1, AQP3, TECR | ESR1 215/4885CACNA1F 3713/4885CACNA1D 4435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.