Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PRKX | P51817 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938164 | 0.89 | HPGD (0.47) | HPGDSLC1A2PRKACACDK8GSK3A | |
| SCHEMBL28453112 | 0.82 | FOLH1 (0.44) | PRKACACDK8GSK3AGSK3BPRKX | |
| SCHEMBL27574603 | 0.82 | HPGD (0.69) | HPGDCTRB1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28443884 | 0.80 | HDAC1 (0.46) | HPGDHDAC1HDAC2 | |
| SCHEMBL28767456 | 0.80 | LMNA (0.53) | HPGDSLC1A2PRKACACDK8GSK3A | |
| SCHEMBL9829488 | 0.80 | SLC1A2 (0.53) | HPGDSLC1A2LMNACA1IDO1 | |
| SCHEMBL3940642 | 0.80 | CTRB1 (0.53) | HPGDSLC1A2PRKACACDK8GSK3A | |
| SCHEMBL3941746 | 0.80 | CTRB1 (0.53) | HPGDSLC1A2PRKACACDK8GSK3A | |
| SCHEMBL29167801 | 0.80 | CTRB1 (0.53) | HPGDSLC1A2PRKACACDK8GSK3A | |
| SCHEMBL9829492 | 0.80 | SLC1A2 (0.53) | HPGDSLC1A2LMNACA1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962440-A | ANTICHOLESTEROL AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-05 | — | — | US | disclosed |