Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 5/20 | 0.53 |
| ▸ | PRKACA | P17612 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | PRKX | P51817 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.50 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.50 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.50 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.50 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29167801 | 1.00 | CTRB1 (0.53) | CTRB1PRKACAGSK3AGSK3BPRKX | |
| SCHEMBL3941746 | 1.00 | CTRB1 (0.53) | CTRB1PRKACAGSK3AGSK3BPRKX | |
| SCHEMBL6355600 | 0.90 | CTRB1 (0.50) | CTRB1PRKACAGSK3AGSK3BPRKX | |
| SCHEMBL10818802 | 0.89 | CTRB1 (0.44) | CTRB1PRKACAGSK3AGSK3BPRKX | |
| SCHEMBL6342085 | 0.89 | CTRB1 (0.59) | CTRB1PRKACAGSK3AGSK3BPRKX | |
| SCHEMBL21362720 | 0.86 | CTRB1 (0.50) | CTRB1PRKACAGSK3AGSK3BPRKX | |
| SCHEMBL11203933 | 0.85 | CTRB1 (0.69) | CTRB1PRKACAGSK3AGSK3BPRKX | |
| SCHEMBL13875451 | 0.83 | CES1 (0.42) | CTRB1PRKACAGSK3AGSK3BPRKX | |
| SCHEMBL3132363 | 0.82 | CTRB1 (0.47) | CTRB1PRKACAGSK3AGSK3BPRKX | |
| SCHEMBL15304889 | 0.82 | MEN1 (0.54) | CTRB1PRKACAGSK3AGSK3BPRKX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117647598-A | High performance liquid analysis method for enantiomer of (S) -3-amino tetrahydrofuran and intermediate | 上海司太立制药有限公司 | 2024-03-05 | — | — | CN | claimed |
| CN-117647598-A | High performance liquid analysis method for enantiomer of (S) -3-amino tetrahydrofuran and intermediate | 上海司太立制药有限公司 | 2024-03-05 | — | — | CN | disclosed |
| US-10421734-B1 | Process for the preparation of enantiopure 3-amino tetrahydrofuran and its salts | SAMI LABS LIMITED (IN) | 2019-09-24 | — | — | US | disclosed |
| US-7514573-B2 | Processes for the manufacture of chiral and racemic forms of 3-aminotetrahydrofurans, their salts and derivatives | SAMI LABS LTD (IN) | 2009-04-07 | — | — | US | disclosed |
| US-7514573-B2 | Processes for the manufacture of chiral and racemic forms of 3-aminotetrahydrofurans, their salts and derivatives | SAMI LABS LTD (IN) | 2009-04-07 | — | — | US | disclosed |
| US-7514573-B2 | Processes for the manufacture of chiral and racemic forms of 3-aminotetrahydrofurans, their salts and derivatives | SAMI LABS LTD (IN) | 2009-04-07 | — | — | US | disclosed |
| US-20080255377-A1 | reduction of diesters of aspartic acid, then cyclization with the aid of sulfonic acids, hydrolysis using a base to give 3-(S)-aminotetrahydrofuran as its hydrochloride or p-toluenesulfonate salt, or as base itself | MAJEED MUHAMMED | 2008-10-16 | — | — | US | disclosed |
| US-20080255377-A1 | reduction of diesters of aspartic acid, then cyclization with the aid of sulfonic acids, hydrolysis using a base to give 3-(S)-aminotetrahydrofuran as its hydrochloride or p-toluenesulfonate salt, or as base itself | MAJEED MUHAMMED | 2008-10-16 | — | — | US | disclosed |
| US-20080255377-A1 | reduction of diesters of aspartic acid, then cyclization with the aid of sulfonic acids, hydrolysis using a base to give 3-(S)-aminotetrahydrofuran as its hydrochloride or p-toluenesulfonate salt, or as base itself | MAJEED MUHAMMED | 2008-10-16 | — | — | US | disclosed |
| US-20050043396-A1 | 5-Benzoylamino-1,3-dioxacyclanes, the method for preparing the same and their use as PKC inhibitor | ZEN HAYLEY (CN) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255377-A1 | reduction of diesters of aspartic acid, then cyclization with the aid of sulfonic acids, hydrolysis using a base to give 3-(S)-aminotetrahydrofuran as its hydrochloride or p-toluenesulfonate salt, or as base itself | AASDHPPT, DNPEP, ASNS | CTRB1 1564/4885PRKACA 2730/4885GSK3A 4828/4885 |
| US-10421734-B1 | Process for the preparation of enantiopure 3-amino tetrahydrofuran and its salts | AASDHPPT, AAAS, AADAT | CTRB1 3706/4885PRKACA 4576/4885GSK3A 4577/4885 |
| US-20050043396-A1 | 5-Benzoylamino-1,3-dioxacyclanes, the method for preparing the same and their use as PKC inhibitor | PRKCA, PRKCD, PRKCB | CTRB1 4655/4885PRKACA 9/4885GSK3A 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.