Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.57 |
| ▸ | THRB | P10828 | 8/20 | 0.57 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.56 |
| ▸ | STS | P08842 | 4/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293988 | 1.00 | THRA (0.57) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL4252573 | 0.85 | THRA (0.55) | THRATHRB | |
| SCHEMBL19291196 | 0.85 | THRA (0.55) | THRATHRB | |
| SCHEMBL7708000 | 0.83 | THRA (0.46) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL8479392 | 0.83 | HSD17B3 (0.69) | THRATHRBHSD17B3HAO1 | |
| SCHEMBL11440891 | 0.83 | THRA (0.79) | THRATHRBHSD17B3HAO1 | |
| SCHEMBL17301080 | 0.82 | THRA (0.50) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL7712100 | 0.81 | THRA (0.45) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL7707971 | 0.81 | THRA (0.45) | THRATHRBHSD17B3STSHAO1 | |
| SCHEMBL1640478 | 0.81 | L3MBTL1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |