SCHEMBL8501624

SCHEMBL8501624

Cc1ccc(S(=O)(=O)Oc2c(F)cccc2-c2cccc3c2Cc2ccccc2-3)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
VDR P11473 1/20 0.39
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
DHODH Q02127 1/20 0.37
KMT2A Q03164 5/20 0.36
MEN1 O00255 4/20 0.36
ESR1 P03372 1/20 0.36
GAA P10253 1/20 0.36
ESR2 Q92731 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
HTR6 P50406 1/20 0.34
PTGS2 P35354 2/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8500023 0.86 ALDH1A1 (0.43) ALDH1A1VDRKEAP1NFE2L2DHODH
SCHEMBL8501253 0.83 MEN1 (0.48) ALDH1A1VDRKEAP1NFE2L2DHODH
SCHEMBL8498897 0.80 DHODH (0.40) ALDH1A1VDRKEAP1NFE2L2DHODH
SCHEMBL30620518 0.75 ALDH1A1 (0.42) ALDH1A1VDRKMT2AMEN1ESR1
SCHEMBL8499639 0.75 ALPL (0.40) ALDH1A1KMT2AMEN1GAANPC1
SCHEMBL8501628 0.74 VDR (0.42) ALDH1A1VDRKEAP1NFE2L2DHODH
SCHEMBL3839070 0.74 VDR (0.42) ALDH1A1VDRKEAP1NFE2L2DHODH
SCHEMBL18191279 0.74 PNMT (0.48) ALDH1A1VDRDHODHKMT2AMEN1
SCHEMBL30620509 0.72 KMT2A (0.40) ALDH1A1VDRKEAP1NFE2L2DHODH
SCHEMBL28568070 0.69 PNMT (0.52) ALDH1A1NPC1RAB9ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0956312-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR Corporation (JP) 1999-11-17 EP disclosed
WO-1998033836-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORPORATION (JP) 1998-08-06 WO disclosed