Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943768 | 0.69 | DAO (0.45) | KDM4EALDH1A1KMT2ACES2CES1 | |
| SCHEMBL2742897 | 0.67 | KDM4E (0.45) | KDM4EALDH1A1KMT2A | |
| SCHEMBL722021 | 0.66 | CES2 (0.32) | CES2CES1 | |
| SCHEMBL724067 | 0.65 | L3MBTL1 (0.30) | — | |
| SCHEMBL722509 | 0.65 | ATM (0.33) | — | |
| SCHEMBL209431 | 0.64 | — | — | |
| SCHEMBL2090725 | 0.62 | MAPT (0.40) | KDM4EALDH1A1KMT2ACES2CES1 | |
| SCHEMBL16539971 | 0.62 | ALDH1A1 (0.42) | ALDH1A1KMT2ADAO | |
| SCHEMBL147222 | 0.61 | — | — | |
| SCHEMBL50975 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939398-A | ANTIATHEROSCLEROSIS AGENTS | PFIZER INC. (US) | 1999-08-17 | — | — | US | disclosed |