Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505747 | 0.89 | KMT2A (0.45) | ALDH1A1ALOX15MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL8504856 | 0.88 | ALDH1A1 (0.47) | ALDH1A1ALOX15MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL7583782 | 0.78 | KMT2A (0.42) | ALDH1A1ALOX15MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL8503196 | 0.74 | MEN1 (0.41) | ALDH1A1ALOX15MAPK1KMT2AHTT | |
| SCHEMBL8501886 | 0.72 | NPBWR1 (0.45) | SMN1; SMN2KMT2ANPSR1TP53NPC1 | |
| SCHEMBL8502484 | 0.72 | HPGD (0.48) | ALDH1A1ALOX15MAPK1SMN1; SMN2GAA | |
| SCHEMBL8501881 | 0.68 | ALDH1A1 (0.38) | ALDH1A1ALOX15KMT2AHTTMEN1 | |
| SCHEMBL28520850 | 0.68 | KMT2A (0.64) | ALDH1A1MAPK1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7583160 | 0.67 | KMT2A (0.42) | ALDH1A1ALOX15MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL8504948 | 0.67 | ALDH1A1 (0.37) | ALDH1A1ALOX15KMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |