Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 11/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505745 | 0.89 | KMT2A (0.44) | NPBWR1KMT2AMAPK14CYP19A1CYP11B1 | |
| SCHEMBL8504853 | 0.88 | KMT2A (0.49) | NPBWR1KMT2AMAPK14CYP19A1MAPT | |
| SCHEMBL8503193 | 0.75 | NR4A1 (0.40) | KMT2ACYP19A1TP53SMN1; SMN2NPSR1 | |
| SCHEMBL8504945 | 0.73 | NPBWR1 (0.39) | NPBWR1KMT2ACYP19A1SMN1; SMN2NPSR1 | |
| SCHEMBL27501601 | 0.73 | NPBWR1 (0.56) | NPBWR1SMN1; SMN2MAPT | |
| SCHEMBL8501890 | 0.72 | ALDH1A1 (0.43) | KMT2ACYP11B1CYP11B2TP53SMN1; SMN2 | |
| SCHEMBL7583782 | 0.70 | KMT2A (0.42) | KMT2ATP53SMN1; SMN2NPSR1MAPT | |
| SCHEMBL8526361 | 0.70 | MAPT (0.43) | KMT2ATP53NPSR1MAPT | |
| SCHEMBL28502249 | 0.69 | ALDH1A1 (0.44) | NPBWR1KMT2ACYP19A1TP53 | |
| SCHEMBL8502094 | 0.68 | MEN1 (0.45) | KMT2ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |