Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | RECQL | P46063 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925837 | 0.79 | ALDH1A1 (0.42) | KDM4EALDH1A1MEN1KMT2APKM | |
| SCHEMBL11800568 | 0.76 | KDM4E (0.52) | KDM4ERECQLALDH1A1ALOX15HIF1A | |
| SCHEMBL27911321 | 0.75 | CA12 (0.36) | KDM4ERECQLALDH1A1ALOX15HIF1A | |
| SCHEMBL2071627 | 0.75 | TRPM8 (0.49) | KDM4EALDH1A1TDP1PKMSMN1; SMN2 | |
| SCHEMBL11793624 | 0.75 | SMN1; SMN2 (0.55) | KDM4ERECQLALDH1A1ALOX15HIF1A | |
| SCHEMBL849513 | 0.74 | CHRNA1 (0.40) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6340899 | 0.74 | MCL1 (0.43) | KDM4ERECQLALDH1A1ALOX15HIF1A | |
| SCHEMBL11925050 | 0.73 | SMN1; SMN2 (0.43) | KDM4EALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL13915059 | 0.73 | S100A4 (0.45) | ALDH1A1MEN1HPGDKMT2APKM | |
| SCHEMBL9674286 | 0.73 | KDM4E (0.48) | KDM4ERECQLALDH1A1ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414730-B1 | Chemical Compounds and pharmaceutical compositions capable of releasing a drug | MILLS RANDELL L (US) | 1999-12-15 | — | — | EP | disclosed |