Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 6/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | STAMBP | O95630 | 1/20 | 0.39 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500463 | 0.76 | PARP1 (0.43) | PARP1PSMD14STAMBPCOPS5MEN1 | |
| Hydrochloric Acid SCHEMBL8500510 | 0.74 | PARP1 (0.42) | PARP1PSMD14STAMBPCOPS5MEN1 | |
| Hydrochloric Acid SCHEMBL8500414 | 0.74 | PARP1 (0.42) | PARP1PSMD14STAMBPCOPS5MEN1 | |
| SCHEMBL4502232 | 0.74 | MEN1 (0.67) | PARP1PSMD14STAMBPCOPS5MEN1 | |
| SCHEMBL27787232 | 0.73 | PARP1 (0.44) | PARP1PSMD14STAMBPCOPS5MEN1 | |
| Hydrochloric Acid SCHEMBL8499722 | 0.72 | PARP1 (0.43) | PARP1PSMD14STAMBPCOPS5MEN1 | |
| SCHEMBL30596827 | 0.71 | PSMD14 (0.36) | TRPA1PARP1PSMD14STAMBPCOPS5 | |
| SCHEMBL29473502 | 0.69 | GRK6 (0.45) | TRPA1KMT2AGRK6CYP3A4MAPT | |
| SCHEMBL2637178 | 0.69 | GRK6 (0.45) | TRPA1KMT2AGRK6CYP3A4MAPT | |
| SCHEMBL25369029 | 0.67 | TRPA1 (0.41) | TRPA1PARP1MEN1KMT2ALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |