Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | STAMBP | O95630 | 1/20 | 0.40 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8499722 | 0.98 | PARP1 (0.43) | PARP1MEN1KMT2APTPN11PSMD14 | |
| SCHEMBL5372908 | 0.84 | MEN1 (0.63) | MEN1KMT2APTPN11PSMD14TSHR | |
| SCHEMBL5372977 | 0.82 | KMT2A (0.43) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL4502232 | 0.79 | MEN1 (0.67) | PARP1MEN1KMT2APTPN11PSMD14 | |
| SCHEMBL8766190 | 0.78 | CA12 (0.46) | MEN1KMT2APTPN11PSMD14LCK | |
| SCHEMBL23292914 | 0.74 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL8502124 | 0.73 | TRPA1 (0.40) | PARP1MEN1KMT2APTPN11PSMD14 | |
| Hydrochloric Acid SCHEMBL8500475 | 0.72 | PTPN11 (0.40) | PTPN11PSMD14STAMBPCOPS5LCK | |
| SCHEMBL120783 | 0.71 | ALDH1A1 (0.40) | MEN1KMT2ATSHRPOLBCYP3A4 | |
| SCHEMBL5376089 | 0.71 | MPO (0.41) | MEN1KMT2ATSHRPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541811-B | Pyrazolopyrimidine Derivatives | DAIICHI SANKYO CO LTD | 2014-07-09 | — | — | CN | disclosed |
| CN-101541811-A | Pyrazolopyrimidine Derivatives | DAIICHI SANKYO CO LTD (JP) | 2009-09-23 | — | — | CN | disclosed |