SCHEMBL2637178

SCHEMBL2637178

C1=Nc2cccc3cccc1c23

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRK6 P43250 1/20 0.45
TRPA1 O75762 8/20 0.43
NSD2 O96028 6/20 0.42
MAPT P10636 5/20 0.40
KDM4E B2RXH2 4/20 0.40
HPGD P15428 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
CYP1B1 Q16678 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HTT P42858 1/20 0.38
RECQL P46063 1/20 0.38
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.37
KMT2A Q03164 1/20 0.37
GAA P10253 1/20 0.34
MCL1 Q07820 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29473502 1.00 GRK6 (0.45) GRK6TRPA1NSD2MAPTKDM4E
SCHEMBL30094137 0.92 GRK6 (0.40) GRK6TRPA1NSD2MAPTKDM4E
Carbazole SCHEMBL28802619 0.82 ALDH1A1 (0.45) GRK6TRPA1KDM4EHPGDALDH1A1
SCHEMBL31468738 0.79 GRK6 (0.36) GRK6TRPA1NSD2MAPTKDM4E
SCHEMBL11858230 0.79 GRK6 (0.36) GRK6TRPA1NSD2MAPTKDM4E
SCHEMBL30881967 0.77 GRK6 (0.42) GRK6NSD2MAPTKDM4EHPGD
SCHEMBL4513619 0.71 ALDH1A1 (0.44) TRPA1HPGDALDH1A1CYP1A2TSHR
SCHEMBL4507288 0.71 ALDH1A1 (0.44) GRK6TRPA1NSD2HPGDALDH1A1
SCHEMBL9926021 0.71 TRPA1 (0.58) TRPA1MAPTHTTKMT2A
SCHEMBL4499327 0.71 TRPA1 (0.36) TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024146635-A1 USE OF PHOTOINITIATOR COMPOSITION IN PHOTOPOLYMERIZATION AT WAVELENGTH OF 200 NM TO LESS THAN 700 NM 湖北固润科技股份有限公司 2024-07-11 WO claimed
CN-116239515-A Fluorescent probe and preparation method and application thereof 苏州大学 2023-06-09 CN claimed
EP-3664892-A2 TUNABLE LUMINESCENT ORGANIC SALTS FOR ENHANCED IMAGING AND PHOTODYNAMIC THERAPY Board of Trustees of Michigan State University (US) 2020-06-17 EP claimed
WO-2019032683-A2 TUNABLE LUMINESCENT ORGANIC SALTS FOR ENHANCED IMAGING AND PHOTODYNAMIC THERAPY BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2019-02-14 WO claimed
EP-1997475-A2 Composition comprising at least one substituted derivative of acetylenic carbocyanine, method of treating keratinous fibres implementing it and device L'Oréal (FR) 2008-12-03 EP claimed
EP-0767809-B1 CURE-INDICATING MOLDING AND COATING COMPOSITION MINNESOTA MINING & MFG (US) 2004-01-21 EP claimed
JP-60083236-A None JP disclosed
US-20260144876-A1 TUNABLE LUMINESCENT ORGANIC SALTS FOR ENHANCED IMAGING AND PHOTODYNAMIC THERAPY BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2026-05-28 US disclosed
US-12478677-B2 Tunable luminescent organic salts for enhanced imaging and photodynamic therapy BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2025-11-25 US disclosed
US-12341465-B2 Photovoltaic devices for switchable windows ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-06-24 US disclosed
WO-2024146635-A1 USE OF PHOTOINITIATOR COMPOSITION IN PHOTOPOLYMERIZATION AT WAVELENGTH OF 200 NM TO LESS THAN 700 NM 湖北固润科技股份有限公司 2024-07-11 WO disclosed
WO-2023189799-A1 SELF CROSS-LINKABLE POLYMER AND RESIST UNDERLAYER FILM-FORMING COMPOSITION 日産化学株式会社 2023-10-05 WO disclosed
US-11738095-B2 Cyanine-containing compounds for cancer imaging and treatment EMORY UNIVERSITY (US) 2023-08-29 US disclosed
EP-1314981-A3 Benzo[c,d]indole-fluorochromes for labelling biomolecules and polymer particles Chromeon GmbH (DE) 2003-07-30 EP disclosed
EP-1314981-A2 Benzo[c,d]indole-fluorochromes for labelling biomolecules and polymer particles Chromeon GmbH (DE) 2003-05-28 EP disclosed
JP-S6083236-A OPTICAL INFORMATION RECORDING MEDIUM RICOH CO LTD 1985-05-11 JP disclosed
US-4087241-A CATIONIC DYES, SOLVENT, NEUTRAL RESIN BAYER AKTIENGESELLSCHAFT (DT) 1978-05-02 US disclosed
US-4000130-A INDOLE DYES, POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed
US-3999939-A SUBLIMABLE CARBINOL BASE DERIVATIVES OF CATIONIC DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed
US-3992140-A Printing inks for transfer printing BAYER AKTIENGESELLSCHAFT (DT) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144876-A1 TUNABLE LUMINESCENT ORGANIC SALTS FOR ENHANCED IMAGING AND PHOTODYNAMIC THERAPY SLC10A6, ACTB, SLC6A6 GRK6 4579/4885TRPA1 74/4885NSD2 2107/4885
US-11738095-B2 Cyanine-containing compounds for cancer imaging and treatment MKI67, MCL1, TP53 GRK6 2787/4885TRPA1 3191/4885NSD2 1803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.