Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.30 |
| ▸ | CCR3 | P51677 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501052 | 0.98 | NPSR1 (0.33) | NPSR1HPGDGAACHRM1MTTP | |
| SCHEMBL8665883 | 0.94 | NPSR1 (0.37) | NPSR1CHRM1DRD2DRD4POLB | |
| SCHEMBL8485545 | 0.92 | NPSR1 (0.40) | NPSR1GAAPOLBCARM1PRMT6 | |
| SCHEMBL8666099 | 0.92 | NPSR1 (0.36) | NPSR1CHRM1DRD2DRD4POLB | |
| SCHEMBL8502242 | 0.90 | NPSR1 (0.35) | NPSR1HPGDGAACHRM1POLB | |
| SCHEMBL8484461 | 0.90 | NPSR1 (0.39) | NPSR1GAAPOLBCARM1PRMT6 | |
| SCHEMBL8501003 | 0.89 | CTSL (0.36) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL8504383 | 0.87 | CCR3 (0.38) | DRD2DRD4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8669690 | 0.84 | UTS2R (0.39) | NPSR1HPGDGAACHRM1DRD2 | |
| SCHEMBL8665495 | 0.84 | CCR2 (0.35) | NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | claimed |
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |