Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668077 | 0.93 | OPRK1 (0.32) | OPRK1 | |
| SCHEMBL8485124 | 0.91 | OPRK1 (0.33) | OPRK1 | |
| SCHEMBL8502242 | 0.81 | NPSR1 (0.35) | MEN1KMT2ANPSR1 | |
| SCHEMBL8480413 | 0.81 | TMEM97 (0.35) | OPRK1 | |
| SCHEMBL8485150 | 0.80 | L3MBTL1 (0.41) | OPRK1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL8502235 | 0.79 | AOC3 (0.32) | NPSR1 | |
| SCHEMBL8503706 | 0.78 | SCN1A (0.31) | — | |
| SCHEMBL8669690 | 0.77 | UTS2R (0.39) | MEN1KMT2ANPSR1 | |
| SCHEMBL8503796 | 0.77 | AOC3 (0.30) | — | |
| SCHEMBL8485599 | 0.77 | MTR (0.38) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |