Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711360 | 0.78 | RAB9A (0.75) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15974627 | 0.78 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15974201 | 0.76 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9329501 | 0.76 | ALDH1A1 (0.64) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8505276 | 0.75 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2216212 | 0.74 | ALDH1A1 (1.00) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4341460 | 0.73 | ERCC5 (0.72) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL23855456 | 0.72 | — | — | |
| SCHEMBL5762863 | 0.72 | GSK3B (0.66) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3242851 | 0.72 | HDAC1 (0.64) | ALDH1A1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939398-A | ANTIATHEROSCLEROSIS AGENTS | PFIZER INC. (US) | 1999-08-17 | — | — | US | disclosed |