Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 9/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15918883 | 0.71 | GRM2 (0.38) | NPSR1MEN1KMT2ACYP2C9 | |
| SCHEMBL7353628 | 0.67 | MMP2 (0.42) | PTGDR2NPSR1MEN1MAPTKMT2A | |
| SCHEMBL7353635 | 0.67 | MMP2 (0.42) | PTGDR2NPSR1MEN1MAPTKMT2A | |
| SCHEMBL8690818 | 0.67 | MMP2 (0.42) | PTGDR2NPSR1MEN1MAPTKMT2A | |
| SCHEMBL5916381 | 0.66 | LMNA (0.44) | MEN1KMT2AKDM4EFFAR1CYP2C9 | |
| SCHEMBL8692922 | 0.66 | ALDH1A1 (0.40) | PPARGPPARAMAPTGAA | |
| SCHEMBL8505443 | 0.66 | ALDH1A1 (0.40) | PPARGPPARAMAPTGAA | |
| SCHEMBL8688113 | 0.66 | ALDH1A1 (0.40) | PPARGPPARAMAPTGAA | |
| SCHEMBL10803560 | 0.66 | CYP2C9 (0.49) | MAPTKMT2AGAAFFAR1CYP2C9 | |
| SCHEMBL27594813 | 0.65 | RIPK1 (0.43) | MEN1KMT2AGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939583-A | ANTIARTHRITIC AGENTS; BONE, CARDIOVASCULAR, BRAIN, NERVOUS SYSTEM DISORDERS; ANTITUMOR AND ANTIMETASTASIS AGENTS | BAYER CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |