Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 18/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | HEXB | P07686 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7863542 | 0.99 | TDP1 (0.38) | TDP1RXRAHASPINDYRK2HEXA | |
| Hydrochloric Acid SCHEMBL7868687 | 0.86 | TDP1 (0.37) | TDP1RXRAHEXAHEXB | |
| SCHEMBL7875394 | 0.76 | NPY5R (0.37) | TDP1 | |
| SCHEMBL7868691 | 0.76 | IDO1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL7868690 | 0.75 | NR3C1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7868709 | 0.75 | IDO1 (0.36) | — | |
| SCHEMBL7863452 | 0.74 | DRD2 (0.44) | TDP1 | |
| SCHEMBL7870296 | 0.71 | ALDH1A1 (0.47) | TDP1 | |
| SCHEMBL8713347 | 0.68 | HTR1A (0.34) | — | |
| SCHEMBL7863446 | 0.65 | HTT (0.39) | TDP1RXRAHASPINDYRK2HEXA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958942-A | HAVING EXCELLENT PDGF-INHIBITING ACTIVITIES, ANTIHYPERTENSIVE ACTIVITIES, ACTIVITIES OF AMELIORATING RENAL DISEASES AND ACTIVITIES OF LOWERING LIPID LEVEL. | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-28 | — | — | US | disclosed |