SCHEMBL1127238

SCHEMBL1127238

CC(=Cc1ccccc1)[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 6/20 1.00
ALDH1A1 P00352 3/20 0.62
LMNA P02545 2/20 0.62
MAPT P10636 2/20 0.62
MEN1 O00255 1/20 0.62
JAK2 O60674 1/20 0.62
MITF O75030 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
NTSR1 P30989 1/20 0.62
CYP2C19 P33261 1/20 0.62
KMT2A Q03164 1/20 0.62
PRMT1 Q99873 1/20 0.58
ABL1 P00519 1/20 0.58
EGFR P00533 1/20 0.58
ABL2 P42684 1/20 0.58
TSHR P16473 1/20 0.50
AKR1C3 P42330 1/20 0.50
RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1032131 1.00 FBP1 (1.00) FBP1ALDH1A1LMNAMAPTMEN1
SCHEMBL1749791 1.00 FBP1 (1.00) FBP1ALDH1A1LMNAMAPTMEN1
SCHEMBL8624866 0.84 FBP1 (0.72) FBP1ALDH1A1LMNAMAPTMEN1
SCHEMBL17558901 0.84 FBP1 (0.72) FBP1ALDH1A1LMNAMAPTMEN1
SCHEMBL8624865 0.84 FBP1 (0.72) FBP1ALDH1A1LMNAMAPTMEN1
SCHEMBL19397776 0.84 FBP1 (0.72) FBP1ALDH1A1LMNAMAPTMEN1
SCHEMBL17558902 0.84 FBP1 (0.72) FBP1ALDH1A1LMNAMAPTMEN1
SCHEMBL2746679 0.82 FBP1 (0.69) FBP1ALDH1A1LMNAMAPTMEN1
SCHEMBL10664676 0.82 FBP1 (0.69) FBP1ALDH1A1LMNAMAPTMEN1
SCHEMBL2746675 0.82 FBP1 (0.69) FBP1ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
CN-115851778-B Thermophilic alkene reductase from aspergillus flavus, expression vector and application thereof 河南工业大学 2024-10-01 CN claimed
CN-115851778-A Thermophilic alkene reductase from aspergillus flavus, expression vector and application thereof 河南工业大学 2023-03-28 CN claimed
CN-111116613-B Polysubstituted benzimidazole thiazole and derivative and synthesis method thereof 湘潭大学 2021-04-23 CN claimed
CN-109096167-A A kind of more carbonyl official substituted chiral pyrrolidin derivatives and preparation method thereof 杭州师范大学 2018-12-28 CN claimed
CN-107417868-A Dispersant of acrylate phenyl nitro propylene copolymer and preparation method thereof 苏州博纳化学科技有限公司 2017-12-01 CN claimed
CN-106117113-A Polysubstituted carbazole, derivant and synthetic method thereof 湘潭大学 2016-11-16 CN claimed
EP-2982368-A1 Small molecule compounds displacing focal adhesion core components Universität Konstanz (DE) 2016-02-10 EP claimed
CN-104142370-B Analysis and detection method of 1-phenyl-2-nitropropene and related substances thereof NANJING TECH UNIVERSITY (CN) 2016-01-06 CN claimed
CN-105188918-A Use of particular metal accumulating plants for carrying out catalytic chemical reactions CENTRE NAT RECH SCIENT 2015-12-23 CN claimed
CN-104142370-A Analysis and detection method of 1-phenyl-2-nitropropene and related substances thereof NANJING UNIVERSITY OF TECHNOLOGY 2014-11-12 CN claimed
US-8791273-B2 4R,5S-enantiomer of 2-(5-methyl-2-oxo-4-phenyl-pyrrolidin-1-yl)-acetamide with nootropic activity JSC GRINDEKS (LV) 2014-07-29 US claimed
EP-2694474-A1 4R,5R-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY Grindeks (LV) 2014-02-12 EP claimed
EP-2496555-B1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY GRINDEKS JSC (LV) 2013-08-28 EP claimed
WO-2012123358-A1 4R,5R-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY GRINDEKS (LV) 2012-09-20 WO claimed
EP-2496555-A1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY Grindeks, A Joint Stock Company (LV) 2012-09-12 EP claimed
US-20120215010-A1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY JSC GRINDEKS (LV) 2012-08-23 US claimed
WO-2011054888-A1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY GRINDEKS, A JOINT STOCK COMPANY (LV) 2011-05-12 WO claimed
US-4220804-A EXPLOSIVES, PLASTICIZERS, BINDERS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1980-09-02 US claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US disclosed
CN-115851778-B Thermophilic alkene reductase from aspergillus flavus, expression vector and application thereof 河南工业大学 2024-10-01 CN disclosed
CN-116284019-B Preparation method of medical intermediate furo [3,2-c ] pyridine-4 (5H) -ketone derivative 安徽工业大学 2024-08-09 CN disclosed
CN-117355512-A Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer 托雷莫治疗股份公司 2024-01-05 CN disclosed
CN-116284019-A Preparation method of medical intermediate furo [3,2-c ] pyridine-4 (5H) -ketone derivative 安徽工业大学 2023-06-23 CN disclosed
US-20230117370-A1 REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS OREGON STATE UNIVERSITY (US) 2023-04-20 US disclosed
CN-115851778-A Thermophilic alkene reductase from aspergillus flavus, expression vector and application thereof 河南工业大学 2023-03-28 CN disclosed
WO-2023034413-A2 METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-09 WO disclosed
CN-115746692-A Low dielectric coating and preparation method thereof 上谷新材料(苏州)有限公司 2023-03-07 CN disclosed
CN-109311876-B Heteroaryl estrogen receptor modulators and uses thereof 豪夫迈·罗氏有限公司 2022-05-03 CN disclosed
WO-2021211982-A2 REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS OREGON STATE UNIVERSITY (US) 2021-10-21 WO disclosed
US-20210137884-A1 INHIBITORS OF METALLO-BETA-LACTAMASES OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2021-05-13 US disclosed
CN-111116613-B Polysubstituted benzimidazole thiazole and derivative and synthesis method thereof 湘潭大学 2021-04-23 CN disclosed
EP-3342767-B1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARM INC (US) 2021-04-14 EP disclosed
US-10908162-B2 Methods related to volatile compounds in genitourinary cancers THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-02-02 US disclosed
US-20200392123-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. 2020-12-17 US disclosed
CN-108329248-B Preparation method of 2-methylindoline 北京成宇化工有限公司 2020-10-30 CN disclosed
US-10689372-B2 Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2020-06-23 US disclosed
CN-104610267-B Method for efficiently synthesizing 6-alkyl pyrazolo [1,5-c ] quinazoline framework compound under non-catalytic condition 江西师范大学 2020-03-20 CN disclosed
US-10463901-B2 Use of metal-accumulating plants for the preparation of catalysts that can be used in chemical reactions CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2019-11-05 US disclosed
US-20190270731-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. 2019-09-05 US disclosed
CN-107235992-B Indolone spiral shell thiophane class compound and its salt, preparation method and application 中国人民解放军第四军医大学 2019-08-20 CN disclosed
CN-106117113-B Polysubstituted carbazole, derivative and its synthetic method 湘潭大学 2019-08-16 CN disclosed
EP-2504096-B1 USE OF METAL-EXTRACTING PLANTS FOR PREPARING CATALYSTS USEFUL IN CHEMICAL REACTIONS CENTRE NAT RECH SCIENT (FR) 2019-07-24 EP disclosed
US-20190128890-A1 METHODS RELATED TO VOLATILE COMPOUNDS IN GENITOURINARY CANCERS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2019-05-02 US disclosed
EP-2970215-B1 PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBVIE DEUTSCHLAND (DE) 2019-04-17 EP disclosed
CN-106565742-B Indolone spiral shell tetrahydro thio-pyrylium analog derivative and its preparation method and application 中国人民解放军第四军医大学 2019-04-05 CN disclosed
US-10166530-B2 Use of certain transition metal hyperaccumulator plants for reducing organic compounds in a green manner CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2019-01-01 US disclosed
CN-109096167-A A kind of more carbonyl official substituted chiral pyrrolidin derivatives and preparation method thereof 杭州师范大学 2018-12-28 CN disclosed
EP-3342767-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2018-07-04 EP disclosed
US-20180030039-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. 2018-02-01 US disclosed
US-20180015317-A1 USE OF METAL-ACCUMULATING PLANTS FOR THE PREPARATION OF CATALYSTS THAT CAN BE USED IN CHEMICAL REACTIONS UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) 2018-01-18 US disclosed
EP-3260196-A1 USE OF METAL-ACCUMULATING PLANTS FOR PREPARING CATALYSTS USEFUL IN CHEMICAL REACTIONS Centre National De La Recherche Scientifique (FR) 2017-12-27 EP disclosed
CN-107417868-A Dispersant of acrylate phenyl nitro propylene copolymer and preparation method thereof 苏州博纳化学科技有限公司 2017-12-01 CN disclosed
CN-107383005-A The preparation method of the acetic acid of 6 methyl 2 (4 aminomethyl phenyl) imidazo [1,2 a] pyridine 3 华东理工大学 2017-11-24 CN disclosed
US-9744391-B2 Use of metal-accumulating plants for implementing chemical reactions CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-08-29 US disclosed
EP-3177399-A1 USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER CNRS (Centre National de la Recherche Scientifique) (FR) 2017-06-14 EP disclosed
US-20170157594-A1 USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2017-06-08 US disclosed
CN-106795064-A Use of certain transition metal super-accumulating plants for the reduction of organic compounds via the green pathway 国家科研中心 2017-05-31 CN disclosed
US-9663500-B2 Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2017-05-30 US disclosed
US-9656955-B2 Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy ABBVIE INC. (US) 2017-05-23 US disclosed
US-9650334-B2 Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy ABBVIE INC. (US) 2017-05-16 US disclosed
CN-106565742-A Indolone screw tetralin sulfo-pyran derivative and preparing method and application thereof 中国人民解放军第四军医大学 2017-04-19 CN disclosed
CN-106117113-A Polysubstituted carbazole, derivant and synthetic method thereof 湘潭大学 2016-11-16 CN disclosed
US-9452168-B2 Pyrrole antifungal agents F2G LTD (GB) 2016-09-27 US disclosed
CN-104529683-B The preparation method of 1-phenylpropene derivatives 陕西师范大学 2016-08-17 CN disclosed
US-9388345-B2 Hydrocarbon synthesis methods, apparatus, and systems SARTEC CORPORATION (US) 2016-07-12 US disclosed
CN-105413673-A Use of metal accumulating plants for the preparation of catalysts useful in chemical reactions CENTRE NAT RECH SCIENT 2016-03-23 CN disclosed
EP-2982368-A1 Small molecule compounds displacing focal adhesion core components Universität Konstanz (DE) 2016-02-10 EP disclosed
CN-105294591-A High-stereo and highly-enantioselective oxazolinedione compound, preparation method and application thereof UNIV HENAN 2016-02-03 CN disclosed
CN-102821844-B Use of metal accumulating plants for the preparation of catalysts useful in chemical reactions NATIONAL RESEARCH CENTER (FR) 2016-01-27 CN disclosed
WO-2016009116-A1 USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2016-01-21 WO disclosed
CN-104142370-B Analysis and detection method of 1-phenyl-2-nitropropene and related substances thereof NANJING TECH UNIVERSITY (CN) 2016-01-06 CN disclosed
CN-104142370-B Analysis and detection method of 1-phenyl-2-nitropropene and related substances thereof NANJING TECH UNIVERSITY (CN) 2016-01-06 CN disclosed
CN-104142370-B Analysis and detection method of 1-phenyl-2-nitropropene and related substances thereof NANJING TECH UNIVERSITY (CN) 2016-01-06 CN disclosed
EP-2958670-A1 USE OF COMPOSITIONS OBTAINED BY CALCINING PARTICULAR METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CATALYTICAL REACTIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2015-12-30 EP disclosed
CN-105188918-A Use of particular metal accumulating plants for carrying out catalytic chemical reactions CENTRE NAT RECH SCIENT 2015-12-23 CN disclosed
US-20150360066-A1 USE OF METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CHEMICAL REACTIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-12-17 US disclosed
US-9149796-B2 Use of metal-accumulating plants for implementing chemical reactions CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-10-06 US disclosed
CN-103694182-B A kind of preparation method of quinoxaline compound ZHEJIANG ZHONGXIN CHEMICAL CO., LTD. (CN) 2015-09-02 CN disclosed
US-20150238500-A1 PYRROLE ANTIFUNGAL AGENTS F2G LTD (GB) 2015-08-27 US disclosed
US-20150191455-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. 2015-07-09 US disclosed
CN-104610267-A Method for efficiently synthetizing 6-alkylpyrazol-[1,5-c]-quinazoline skeleton compounds under no catalytic condition UNIV JIANGXI NORMAL 2015-05-13 CN disclosed
CN-103570691-B Chiral pyrrolidine functionalized imidazolium salt, and preparation method and application thereof UNIV SHANXI 2015-05-13 CN disclosed
US-9012478-B2 Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2015-04-21 US disclosed
US-8993574-B2 Pyrrole antifungal agents F2G LTD (GB) 2015-03-31 US disclosed
EP-2283006-B1 PYRROLE ANTIFUNGAL AGENTS F2G LTD (GB) 2015-02-25 EP disclosed
CN-104142370-A Analysis and detection method of 1-phenyl-2-nitropropene and related substances thereof NANJING UNIVERSITY OF TECHNOLOGY 2014-11-12 CN disclosed
CN-104142370-A Analysis and detection method of 1-phenyl-2-nitropropene and related substances thereof NANJING UNIVERSITY OF TECHNOLOGY 2014-11-12 CN disclosed
CN-104142370-A Analysis and detection method of 1-phenyl-2-nitropropene and related substances thereof NANJING UNIVERSITY OF TECHNOLOGY 2014-11-12 CN disclosed
EP-2626361-B1 Pyrrole antifungal agents F2G LTD (GB) 2014-10-15 EP disclosed
US-20140296317-A1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY JSC GRINDEKS (LV) 2014-10-02 US disclosed
US-20140275087-A1 PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY AbbVie Deutschland GmbH & Co. KG (DE) 2014-09-18 US disclosed
US-20140275086-A1 PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY AbbVie Deutschland GmbH & Co. KG (DE) 2014-09-18 US disclosed
WO-2014128283-A1 USE OF COMPOSITIONS OBTAINED BY CALCINING PARTICULAR METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CATALYTICAL REACTIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2014-08-28 WO disclosed
EP-2769765-A1 Use of compositions obtained by calcing particular metal-accumulating plants for implementing catalytical reactions Centre National De La Recherche Scientifique (FR) 2014-08-27 EP disclosed
US-8791273-B2 4R,5S-enantiomer of 2-(5-methyl-2-oxo-4-phenyl-pyrrolidin-1-yl)-acetamide with nootropic activity JSC GRINDEKS (LV) 2014-07-29 US disclosed
US-20140171469-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2014-06-19 US disclosed
CN-103788089-A Fused heterocyclic compounds as serotonin receptor modulators JANSSEN PHARMACEUTICA NV 2014-05-14 CN disclosed
CN-103694182-A Preparation method of quinoxaline compound ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2014-04-02 CN disclosed
CN-1882590-B Fused heterocyclic compounds as serotonin receptor modulators JANSSEN PHARMACEUTICA NV 2014-03-05 CN disclosed
US-20140046104-A1 HYDROCARBON SYNTHESIS METHODS, APPARATUS, AND SYSTEMS SARTEC CORPORATION 2014-02-13 US disclosed
EP-2694474-A1 4R,5R-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY Grindeks (LV) 2014-02-12 EP disclosed
CN-103570691-A Chiral pyrrolidine functionalized imidazolium salt, and preparation method and application thereof UNIV SHANXI 2014-02-12 CN disclosed
WO-2014008355-A1 HYDROCARBON SYNTHESIS METHODS, APPARATUS, AND SYSTEMS MCNEFF CLAYTON V (US) 2014-01-09 WO disclosed
EP-2496555-B1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY GRINDEKS JSC (LV) 2013-08-28 EP disclosed
EP-2626361-A1 Pyrrole antifungal agents F2G Limited (GB) 2013-08-14 EP disclosed
CN-101851182-B Salt-free preparation method for substituted taurine UNIV BEIJING CHEMICAL 2013-07-17 CN disclosed
US-20120316340-A1 USE OF METAL-ACCUMULATING PLANTS FOR THE PREPARATION OF CATALYSTS THAT CAN BE USED IN CHEMICAL REACTIONS UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) 2012-12-13 US disclosed
CN-102821844-A Use of metal accumulating plants for the preparation of catalysts useful in chemical reactions CENTRE NAT RECH SCIENT 2012-12-12 CN disclosed
CN-101500994-B 1,3-disubstituted 4-methyl-1h-pyrrole-2-carboxamides and their use for the manufacture of medicaments GRUENENTHAL GMBH 2012-12-12 CN disclosed
CN-101318961-B Fused heterocyclic compound JANSSEN PHARMACEUTICA NV 2012-11-28 CN disclosed
EP-2504096-A1 USE OF METAL-ACCUMULATING PLANTS FOR THE PREPARATION OF CATALYSTS THAT CAN BE USED IN CHEMICAL REACTIONS Centre National de la Recherche Scientifique (FR) 2012-10-03 EP disclosed
WO-2012123358-A1 4R,5R-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY GRINDEKS (LV) 2012-09-20 WO disclosed
EP-2496555-A1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY Grindeks, A Joint Stock Company (LV) 2012-09-12 EP disclosed
US-20120215010-A1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY JSC GRINDEKS (LV) 2012-08-23 US disclosed
EP-2367797-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2011-09-28 EP disclosed
US-20110224262-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2011-09-15 US disclosed
US-7968591-B2 1,3-disubstituted 4-methyl-1H-pyrrole-2-carboxamides and their use in medicaments GRUENENTHAL GMBH (DE) 2011-06-28 US disclosed
US-20110152285-A1 PYRROLE ANTIFUNGAL AGENTS F2G LTD (GB) 2011-06-23 US disclosed
WO-2011064462-A1 USE OF METAL-ACCUMULATING PLANTS FOR THE PREPARATION OF CATALYSTS THAT CAN BE USED IN CHEMICAL REACTIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-06-03 WO disclosed
WO-2011064487-A1 USE OF METAL-ACCUMULATING PLANTS FOR THE PREPARATION OF CATALYSTS THAT CAN BE USED IN CHEMICAL REACTIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-06-03 WO disclosed
WO-2011054888-A1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY GRINDEKS, A JOINT STOCK COMPANY (LV) 2011-05-12 WO disclosed
WO-2011048611-A1 NOVEL FUSED PYRIDAZINE DERIVATIVES TORRENT PHARMACEUTICALS LIMITED (IN) 2011-04-28 WO disclosed
US-7897771-B2 Fused heterocyclic compounds JANSSEN PHARMACEUTICA NV (BE) 2011-03-01 US disclosed
US-20110040088-A1 FUSED HETEROCYCLIC COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2011-02-17 US disclosed
EP-2283006-A1 PYRROLE ANTIFUNGAL AGENTS F2G Limited (GB) 2011-02-16 EP disclosed
CN-101851182-A Salt-free preparation method for substituted taurine UNIV BEIJING CHEMICAL 2010-10-06 CN disclosed
WO-2010068242-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2010-06-17 WO disclosed
US-7723065-B2 Conditions for reactions mediated by yeast VICTORIA UNIVERSITY (AU) 2010-05-25 US disclosed
US-20090270370-A1 FUSED HETEROCYCLIC COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2009-10-29 US disclosed
WO-2009130481-A1 PYRROLE ANTIFUNGAL AGENTS F2G LTD (GB) 2009-10-29 WO disclosed
US-7579470-B2 Fused heterocyclic compounds JANSSEN PHARMACEUTICA NV (BE) 2009-08-25 US disclosed
US-20090208413-A1 Registry Method and Control System for Dea Schedule II-V Medicines DR PHARMA NOVA, LLC 2009-08-20 US disclosed
CN-101500994-A 1,3-disubstituted 4-methyl-1h-pyrrole-2-carboxamides and their use for the manufacture of medicaments GRUENENTHAL CHEMIE (DE) 2009-08-05 CN disclosed
US-20090137573-A1 1,3-Disubstituted 4-methyl-1H-pyrrole-2-carboxamides and their Use in Medicaments GRUENENTHAL GMBH (DE) 2009-05-28 US disclosed
CN-101318961-A Fused heterocyclic compound JANSSEN PHARMACEUTICA NV (BE) 2008-12-10 CN disclosed
CN-101318962-A Fused heterocyclic compound JANSSEN PHARMACEUTICA NV (BE) 2008-12-10 CN disclosed
US-7402680-B2 Fused heterocyclic compounds JANSSEN PHARMACEUTICA, N.V. (BE) 2008-07-22 US disclosed
EP-1944306-A1 Fused heterocyclic compounds as serotonin receptor modulators Janssen Pharmaceutica, N.V. (BE) 2008-07-16 EP disclosed
US-20080103132-A1 FUSED HETEROCYCLIC COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2008-05-01 US disclosed
EP-1905774-A1 Fused heterocyclic compounds as serotonin receptor modulators Janssen Pharmaceutica, N.V. (BE) 2008-04-02 EP disclosed
US-7319130-B2 Phenolic resins ANGUS CHEMICAL COMPANY (US) 2008-01-15 US disclosed
US-7317063-B2 Phenolic resins ANGUS CHEMICAL COMPANY (US) 2008-01-08 US disclosed
EP-1766365-A2 DETECTION OF ANALYTES Platypus Technologies, LLC (US) 2007-03-28 EP disclosed
US-20070055041-A1 Novel phenolic resins SWEDO RAYMOND J 2007-03-08 US disclosed
US-20070004046-A1 Detection of analytes PLATYPUS TECHNOLOGIES, LLC (US) 2007-01-04 US disclosed
WO-2006085971-A2 DETECTION OF ANALYTES PLATYPUS TECHNOLOGIES, LLC (US) 2006-08-17 WO disclosed
EP-1668014-A2 FUSED HETEROCYCLIC COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-14 EP disclosed
CN-1720273-A Novel phenolic resin ANGUS CHEMICAL (US) 2006-01-11 CN disclosed
EP-1569975-A2 PHENOLIC RESINS ANGUS CHEMICAL COMPANY (US) 2005-09-07 EP disclosed
US-20050119295-A1 Fused heterocyclic compounds JANSSEN PHARMACEUTICA, N.V. (BE) 2005-06-02 US disclosed
WO-2005040169-A2 FUSED HETEROCYCLIC COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2005-05-06 WO disclosed
US-20050084943-A1 New conditions for reactions mediated by yeast VICTORIA UNIVERSITY OF TECHNOLOGY (AU) 2005-04-21 US disclosed
US-20040198926-A1 Novel phenolic resins ANGUS CHEMICAL COMPANY 2004-10-07 US disclosed
US-20040116647-A1 Novel phenolic resins ANGUS CHEMICAL COMPANY 2004-06-17 US disclosed
WO-2004050733-A2 PHENOLIC RESINS ANGUS CHEMICAL COMPANY (US) 2004-06-17 WO disclosed
CN-1284066-A Substituted imidazole derivatives having agonist-like activity at alpha 2B or 2B/2C adrenergic receptors ALLERGEN SALES INC (US) 2001-02-14 CN disclosed
EP-0672646-B1 Process for producing beta-nitro-enamines and intermediates thereof SUMITOMO CHEMICAL CO (JP) 1998-06-10 EP disclosed
EP-0613458-B1 ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS PFIZER (US) 1998-01-07 EP disclosed
US-5639895-A Process for producing β-nitroenamine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-17 US disclosed
US-5597940-A REACTING NITROOLEFIN WITH HYDROXYLAMINE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-01-28 US disclosed
US-5521220-A Acyclic ethylenediamine derivatives PFIZER INC. (US) 1996-05-28 US disclosed
EP-0672646-A1 Process for producing beta-nitro-enamines and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-09-20 EP disclosed
EP-0613458-A1 ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS PFIZER INC. (US) 1994-09-07 EP disclosed
WO-1993010073-A1 ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS PFIZER INC. (US) 1993-05-27 WO disclosed
US-5189055-A Antimitotic, anticarcinogenic CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1993-02-23 US disclosed
EP-0300688-A1 Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them FISONS plc (GB) 1989-01-25 EP disclosed
US-4490392-A Benzylalcohol derivative and process for preparing TANABE SEIYAKU CO., LTD. (JP) 1984-12-25 US disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed
US-4414401-A Process for separating and recovering metal catalysts MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-11-08 US disclosed
US-4220804-A EXPLOSIVES, PLASTICIZERS, BINDERS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1980-09-02 US disclosed
US-4196295-A MICROBIOCIDES, CYCLIZATION INTERNATIONAL MINERALS AND CHEMICAL CORPORATION (US) 1980-04-01 US disclosed
US-4148923-A 1-(3'-Trifluoromethylthiophenyl)-2-ethylaminopropane pharmaceutical composition and method for treating obesity SYNTHELABO (FR) 1979-04-10 US disclosed
US-4129598-A ANOREXIGENIC AGENTS SYNTHELABO (FR) 1978-12-12 US disclosed
US-4000197-A FROM PHENYLACETONES AND METHYL BENZYLAMINE, REDUCTION, HYDROGENOLYSIS THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1976-12-28 US disclosed
US-3965190-A ANOREXIGENIC SYNTHELABO (FR) 1976-06-22 US disclosed
US-3965190-A ANOREXIGENIC SYNTHELABO (FR) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (28 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10166530-B2 Use of certain transition metal hyperaccumulator plants for reducing organic compounds in a green manner SLC39A3, OAT, GLB1 FBP1 538/4885ALDH1A1 937/4885LMNA 4356/4885
US-20050119295-A1 Fused heterocyclic compounds TPH1, HTR3A, HTR3B FBP1 1093/4885ALDH1A1 2953/4885LMNA 4255/4885
US-20170157594-A1 USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER SLC39A3, OAT, GLB1 FBP1 538/4885ALDH1A1 937/4885LMNA 4356/4885
US-20110040088-A1 FUSED HETEROCYCLIC COMPOUNDS TPH1, HTR3A, HTR3B FBP1 1093/4885ALDH1A1 2953/4885LMNA 4255/4885
US-20110224262-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO PTGIR, PTGIS, PTGER1 FBP1 2895/4885ALDH1A1 737/4885LMNA 2865/4885
US-20140275086-A1 PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY SLC6A7, GFPT1, SUGT1 FBP1 574/4885ALDH1A1 1275/4885LMNA 4718/4885
US-20090208413-A1 Registry Method and Control System for Dea Schedule II-V Medicines DUT, CNR2, QDPR FBP1 4638/4885ALDH1A1 909/4885LMNA 4081/4885
US-20150360066-A1 USE OF METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CHEMICAL REACTIONS PICALM, CACYBP, SLC39A14 FBP1 837/4885ALDH1A1 4293/4885LMNA 3498/4885
US-20210137884-A1 INHIBITORS OF METALLO-BETA-LACTAMASES MGAM, GAA, ALPI FBP1 288/4885ALDH1A1 210/4885LMNA 1457/4885
US-20150191455-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO PTGIR, PTGIS, PTGER1 FBP1 2895/4885ALDH1A1 737/4885LMNA 2865/4885
US-20140296317-A1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY NAAA, NAT1, NAA15 FBP1 2040/4885ALDH1A1 716/4885LMNA 4183/4885
US-20090270370-A1 FUSED HETEROCYCLIC COMPOUNDS TPH1, HTR3A, HTR3B FBP1 1093/4885ALDH1A1 2953/4885LMNA 4255/4885
US-20140171469-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO PTGIR, PTGIS, PTGER1 FBP1 2895/4885ALDH1A1 737/4885LMNA 2865/4885
US-10689372-B2 Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto PTGIR, PTGIS, PTGER1 FBP1 2895/4885ALDH1A1 737/4885LMNA 2865/4885
US-20180015317-A1 USE OF METAL-ACCUMULATING PLANTS FOR THE PREPARATION OF CATALYSTS THAT CAN BE USED IN CHEMICAL REACTIONS PICALM, MAX, MGAM FBP1 1098/4885ALDH1A1 4394/4885LMNA 3202/4885
US-20080103132-A1 FUSED HETEROCYCLIC COMPOUNDS TPH1, HTR3A, HTR3B FBP1 1093/4885ALDH1A1 2953/4885LMNA 4255/4885
US-20200392123-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO PTGIR, PTGIS, PTGER1 FBP1 2895/4885ALDH1A1 737/4885LMNA 2865/4885
US-20110152285-A1 PYRROLE ANTIFUNGAL AGENTS FOXM1, PYCR1, ARG1 FBP1 136/4885ALDH1A1 219/4885LMNA 3641/4885
US-20040198926-A1 Novel phenolic resins PNMT, NNMT, PNN FBP1 2880/4885ALDH1A1 665/4885LMNA 710/4885
US-20180030039-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO PTGIR, PTGIS, PTGER1 FBP1 2895/4885ALDH1A1 737/4885LMNA 2865/4885
US-20090137573-A1 1,3-Disubstituted 4-methyl-1H-pyrrole-2-carboxamides and their Use in Medicaments OPRL1, TPH1, OPRK1 FBP1 603/4885ALDH1A1 2168/4885LMNA 2854/4885
US-20140275087-A1 PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY SLC6A7, GFPT1, SUGT1 FBP1 574/4885ALDH1A1 1275/4885LMNA 4718/4885
US-20150238500-A1 PYRROLE ANTIFUNGAL AGENTS FOXM1, PYCR1, ARG1 FBP1 136/4885ALDH1A1 219/4885LMNA 3641/4885
US-20190270731-A1 PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO PTGIR, PTGIS, PTGER1 FBP1 2895/4885ALDH1A1 737/4885LMNA 2865/4885
US-20230117370-A1 REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS CYP2B6, TYR, CYP2D6 FBP1 1823/4885ALDH1A1 88/4885LMNA 2835/4885
US-20120215010-A1 4R,5S-ENANTIOMER OF 2-(5-METHYL-2-OXO-4-PHENYL-PYRROLIDIN-1-YL)-ACETAMIDE WITH NOOTROPIC ACTIVITY NAAA, NAT1, NAA15 FBP1 2040/4885ALDH1A1 716/4885LMNA 4183/4885
US-10463901-B2 Use of metal-accumulating plants for the preparation of catalysts that can be used in chemical reactions PICALM, MAX, MGAM FBP1 1098/4885ALDH1A1 4394/4885LMNA 3202/4885
US-20120316340-A1 USE OF METAL-ACCUMULATING PLANTS FOR THE PREPARATION OF CATALYSTS THAT CAN BE USED IN CHEMICAL REACTIONS AS3MT, AGL, ME1 FBP1 246/4885ALDH1A1 736/4885LMNA 3740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.