SCHEMBL146838

SCHEMBL146838

c1ccc([Si]([N][Si](c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
CA12 O43570 1/20 0.37
GLA P06280 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA14 Q9ULX7 1/20 0.37
ALDH1A1 P00352 3/20 0.35
NPC1 O15118 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
TSHR P16473 4/20 0.30
LMNA P02545 2/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49918 0.75 ESR1 (0.42) ESR1ESR2CA1CA2CA9
SCHEMBL49706 0.73 ALDH1A1 (0.43) ESR1ESR2CA1CA2CA9
SCHEMBL1416688 0.73 ESR1 (0.36) ESR1ESR2CA1CA2CA9
SCHEMBL27683515 0.69 ESR1 (0.33) ESR1ESR2
SCHEMBL3275968 0.69 ESR1 (0.33) ESR1ESR2
SCHEMBL2786417 0.69 ESR1 (0.33) ESR1ESR2
SCHEMBL842861 0.69 ESR1 (0.42) ESR1ESR2ALDH1A1NPC1RAB9A
SCHEMBL842023 0.69 ESR1 (0.42) ESR1ESR2ALDH1A1NPC1RAB9A
SCHEMBL7628154 0.68 ESR1 (0.32) ESR1ESR2
SCHEMBL242095 0.67 ALDH1A1 (0.40) ESR1ESR2CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011526957-A 2011-10-20 JP claimed
EP-2307461-A1 POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP Bridgestone Corporation (JP) 2011-04-13 EP claimed
WO-2010002849-A1 POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2010-01-07 WO claimed
US-20100004414-A1 POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2010-01-07 US claimed
EP-3442045-B1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR BATTERY MODULE AND SENSOR PROVIDED WITH SAME SUMITOMO CHEMICAL CO (JP) 2022-01-12 EP disclosed
US-11063219-B2 Organic photoelectric conversion element, and solar cell module and sensor provided with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-07-13 US disclosed
US-10777746-B2 Compound and electronic device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-09-15 US disclosed
US-10290809-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-05-14 US disclosed
US-20190115540-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL MODULE AND SENSOR PROVIDED WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-18 US disclosed
EP-3442045-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR BATTERY MODULE AND SENSOR PROVIDED WITH SAME Sumitomo Chemical Company, Limited (JP) 2019-02-13 EP disclosed
EP-3412696-A1 HIGH-MOLECULAR COMPOUNDS AND POLYMER LIGHT EMITTING DEVICES MADE BY USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-12-12 EP disclosed
EP-1571170-B1 HIGH-MOLECULAR COMPOUNDS AND POLYMER LIGHT EMITTING DEVICES MADE BY USING THE SAME SUMITOMO CHEMICAL CO (JP) 2018-09-05 EP disclosed
US-20100004414-A1 POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2010-01-07 US disclosed
US-20090039765-A1 LIGHT EMITTING POLYMER COMPOSITION AND POLYMER LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-12 US disclosed
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-12 US disclosed
US-20080003422-A1 Polymer Compound, Polymer Thin Film and Polymer Thin Film Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20070063190-A1 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070020479-A1 Luminescent-polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-25 US disclosed
EP-1571170-A1 HIGH-MOLECULAR COMPOUNDS AND POLYMER LIGHT EMITTING DEVICES MADE BY USING THE SAME Sumitomo Chemical Company, Limited (JP) 2005-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090039765-A1 LIGHT EMITTING POLYMER COMPOSITION AND POLYMER LIGHT EMITTING DEVICE CYBA, BCAT1, CRY1 ESR1 843/4885ESR2 2107/4885CA1 3968/4885
US-10290809-B2 Macromolecular compound EXOSC4, TRPC6, MRPS22 ESR1 1200/4885ESR2 1642/4885CA1 2983/4885
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties BRS3, SLC43A1, MRPS23 ESR1 1141/4885ESR2 903/4885CA1 2303/4885
US-20070063190-A1 Aromatic compound AHR, AR, NR0B1 ESR1 439/4885ESR2 241/4885CA1 3946/4885
US-20100004414-A1 POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP PARG, PIN1, NPEPPS ESR1 3255/4885ESR2 4131/4885CA1 2875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.