Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 6/20 | 0.75 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.75 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.75 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.75 |
| ▸ | F2 | P00734 | 4/20 | 0.75 |
| ▸ | F10 | P00742 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851801 | 0.86 | F10 (1.00) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851549 | 0.80 | ST14 (0.71) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851168 | 0.78 | ST14 (1.00) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851757 | 0.76 | ST14 (0.81) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL1424658 | 0.75 | KMT2A (0.57) | KMT2AMEN1TDP1GLO1POLB | |
| SCHEMBL8009202 | 0.73 | KMT2A (0.65) | KMT2AMEN1TDP1GLO1POLB | |
| SCHEMBL852138 | 0.73 | ST14 (1.00) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6295991 | 0.72 | PRSS1 (0.68) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL851794 | 0.72 | F10 (1.00) | ST14PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6979087 | 0.71 | TDP1 (1.00) | KMT2AMEN1TDP1GLO1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |