Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ULK1 | O75385 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL76440 | 0.98 | SCN3A (0.57) | RAB9ANPC1SCN3ASCN9APSMB8 | |
| Hydrochloric Acid SCHEMBL76439 | 0.98 | SCN3A (0.57) | RAB9ANPC1SCN3ASCN9APSMB8 | |
| SCHEMBL2170910 | 0.92 | PFKFB3 (0.53) | RAB9ANPC1SCN3ASCN9APSMB8 | |
| SCHEMBL23373329 | 0.92 | PFKFB3 (0.53) | RAB9ANPC1SCN3ASCN9APSMB8 | |
| SCHEMBL13388756 | 0.87 | SCN3A (0.64) | RAB9ASCN3ASCN9APSMB8ULK1 | |
| SCHEMBL7692273 | 0.86 | SCN3A (0.56) | SCN3ASCN9APSMB8HTTULK1 | |
| SCHEMBL29365790 | 0.86 | SCN3A (0.56) | SCN3ASCN9APSMB8HTTULK1 | |
| SCHEMBL13379539 | 0.84 | SCN3A (0.58) | RAB9ANPC1SCN3ASCN9APSMB8 | |
| SCHEMBL1750392 | 0.84 | SCN3A (0.58) | RAB9ANPC1SCN3ASCN9APSMB8 | |
| SCHEMBL873241 | 0.84 | SCN3A (0.55) | RAB9ANPC1SCN3ASCN9APSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053541-A1 | COMPOUNDS FOR USE AS APPETITE SUPPRESSANT | ERACAL THERAPEUTICS LTD. (CH) | 2022-03-17 | — | — | WO | disclosed |
| US-8129373-B2 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7906516-B2 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20100256131-A1 | CARBONYL COMPOUNDS | TSAKLAKIDIS CHRISTOS | 2010-10-07 | — | — | US | disclosed |
| CN-101102818-A | Medicaments comprising carbonyl compounds, and the use thereof | MERCK PATENT GMBH (DE) | 2008-01-09 | — | — | CN | disclosed |
| US-20080003214-A1 | Medicaments Comprising Carbonyl Compounds, And The Use Thereof | MERCK PATENT GMBH (DE) | 2008-01-03 | — | — | US | disclosed |
| WO-2006032342-A2 | CARBONYL COMPOUND-CONTAINING DRUG AND THE USE THEREOF | MERCK PATENT GMBH (DE) | 2006-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256131-A1 | CARBONYL COMPOUNDS | F2, F11, PDHX | RAB9A 1813/4885NPC1 2731/4885SCN3A 4518/4885 |
| US-20080003214-A1 | Medicaments Comprising Carbonyl Compounds, And The Use Thereof | F2, PDHX, SDHB | RAB9A 3292/4885NPC1 1383/4885SCN3A 4340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.