SCHEMBL1890981

SCHEMBL1890981

CCCC#Cc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ DPYD Q12882 4/20 0.50
▸ ATAD2 Q6PL18 1/20 0.41
▸ GAA P10253 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ LMNA P02545 1/20 0.37
▸ CYP19A1 P11511 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ THPO P40225 1/20 0.37
▸ MTOR P42345 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ HBB P68871 1/20 0.37
▸ PMP22 Q01453 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1050748 0.90 DPYD (0.47) DPYDATAD2GAAMAPTALDH1A1
SCHEMBL16585678 0.87 GPR84 (0.46) DPYDATAD2MAPTALDH1A1TSHR
SCHEMBL3485393 0.86 DPYD (0.53) DPYDATAD2GAAMAPTALDH1A1
SCHEMBL887754 0.83 DPYD (0.50) DPYDATAD2GAAMAPTALDH1A1
SCHEMBL16586721 0.80 GPR84 (0.43) DPYDMAPTLMNATSHRSMN1; SMN2
SCHEMBL16586691 0.80 GPR84 (0.43) DPYDMAPTLMNATSHRSMN1; SMN2
SCHEMBL30504798 0.80 DPYD (0.44) DPYDATAD2GAAMAPTALDH1A1
SCHEMBL31045516 0.79 DPYD (0.54) DPYDATAD2GAAMAPTALDH1A1
SCHEMBL17553298 0.79 DPYD (0.46) DPYDATAD2GAAMAPTALDH1A1
SCHEMBL2001029 0.79 DPYD (0.53) DPYDATAD2GAAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5840867-A Aptamer analogs specific for biomolecules GILEAD SCIENCES, INC. (US) 1998-11-24 — — US claimed
WO-1992014842-A1 APTAMERS SPECIFIC FOR THROMBIN AND METHODS OF USE GILEAD SCIENCES, INC. (US) 1992-09-03 — — WO claimed
US-12146891-B2 United states systems and methods for fluid and component handling LABRADOR DIAGNOSTICS LLC (US) 2024-11-19 — — US disclosed
US-12085583-B2 Systems and methods for multi-analysis LABRADOR DIAGNOSTICS LLC (US) 2024-09-10 — — US disclosed
EP-4220120-A2 SYSTEMS AND METHODS FOR MULTI-ANALYSIS Labrador Diagnostics LLC (US) 2023-08-02 — — EP disclosed
US-11644410-B2 Systems and methods for sample use maximization LABRADOR DIAGNOSTICS LLC (US) 2023-05-09 — — US disclosed
EP-2956754-B1 SYSTEMS AND METHODS FOR MULTI-ANALYSIS LABRADOR DIAGNOSTICS LLC (US) 2023-01-11 — — EP disclosed
US-11524299-B2 Systems and methods for fluid handling LABRADOR DIAGNOSTICS LLC (US) 2022-12-13 — — US disclosed
CN-114994342-A System and method for multivariate analysis 赛拉诺斯知识产权有限责任公司 2022-09-02 — — CN disclosed
US-20220252503-A1 SYSTEMS AND METHODS FOR SAMPLE USE MAXIMIZATION LABRADOR DIAGNOSTICS LLC (US) 2022-08-11 — — US disclosed
EP-4024029-A2 SYSTEMS AND METHODS FOR SAMPLE USE MAXIMIZATION Labrador Diagnostics LLC (US) 2022-07-06 — — EP disclosed
WO-1996020277-A2 RECOMBINANT MONOCLONAL ANTI-IDIOTYPE ANTIBODY 3H1 SEQUENCES RELATING TO HUMAN CARCINOEMBRYONIC ANTIGEN UNIVERSITY OF KENTUCKY (US) 1996-07-04 — — WO disclosed
WO-1995020317-A1 METHOD FOR MAKING UNIVERSAL DONOR CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-08-03 — — WO disclosed
WO-1995004064-A9 POLYNUCLEOTIDE DECOYS THAT IHNIBIT MHC-II EXPRESSION AND USES THEREOF — 1995-03-09 — — WO disclosed
WO-1995004064-A1 POLYNUCLEOTIDE DECOYS THAT IHNIBIT MHC-II EXPRESSION AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-02-09 — — WO disclosed
EP-0626852-A1 METHOD FOR MAKING UNIVERSAL DONOR CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-12-07 — — EP disclosed
EP-0572529-A1 APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING GILEAD SCIENCES, INC. (US) 1993-12-08 — — EP disclosed
WO-1993014769-A1 METHOD FOR MAKING UNIVERSAL DONOR CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-08-05 — — WO disclosed
WO-1992014842-A1 APTAMERS SPECIFIC FOR THROMBIN AND METHODS OF USE GILEAD SCIENCES, INC. (US) 1992-09-03 — — WO disclosed
WO-1992014843-A1 APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING GILEAD SCIENCES, INC. (US) 1992-09-03 — — WO disclosed
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