Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.55 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.55 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513503 | 0.90 | PRSS1 (0.56) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL3792439 | 0.84 | ST14 (0.77) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL852134 | 0.81 | ST14 (0.76) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL8508906 | 0.74 | PRSS1 (0.65) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL3798064 | 0.74 | PRSS1 (0.78) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL851310 | 0.72 | ST14 (1.00) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL851552 | 0.71 | ST14 (0.71) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL3790598 | 0.69 | PRSS1 (0.78) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL15705237 | 0.67 | FFAR1 (0.68) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL851537 | 0.67 | ST14 (0.72) | PRSS1PRSS2PRSS3ST14F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2014-07-17 | — | — | US | disclosed |
| US-20120136002-A1 | PROTEASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | PRSS1 3/4885PRSS2 23/4885PRSS3 11/4885 |
| US-20120136002-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | PRSS1 3/4885PRSS2 23/4885PRSS3 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.