SCHEMBL8510326

SCHEMBL8510326

FC(F)(F)c1c(S)c(C(F)(F)F)c(Br)c(C(F)(F)F)c1Br

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22115543 0.84 GPR35 (0.33) GPR35
SCHEMBL8512489 0.74
SCHEMBL8514267 0.72 SOS1 (0.33)
SCHEMBL8513822 0.67 NOTUM (0.36)
SCHEMBL28504162 0.65 NOTUM (0.34)
SCHEMBL16799532 0.63 GPR35 (0.39) GPR35
SCHEMBL8513191 0.61 NOTUM (0.37)
SCHEMBL28504665 0.61 TSHR (0.31)
SCHEMBL1995717 0.61 SMN1; SMN2 (0.35)
SCHEMBL30377798 0.61 TSHR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877869-B2 Method for selecting organic sulfur compound for golf ball, method for producing golf ball, and golf ball SRI SPORTS LIMITED (JP) 2014-11-04 US disclosed
US-20120135823-A1 METHOD FOR SELECTING ORGANIC SULFUR COMPOUND FOR GOLF BALL, METHOD FOR PRODUCING GOLF BALL, AND GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120135823-A1 METHOD FOR SELECTING ORGANIC SULFUR COMPOUND FOR GOLF BALL, METHOD FOR PRODUCING GOLF BALL, AND GOLF BALL GIGYF2, FKBP4, GSS GPR35 3886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.