SCHEMBL8510366

SCHEMBL8510366

C1=CCC(c2ccccc2)C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.48
SIGMAR1 Q99720 1/20 0.48
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
TSHR P16473 1/20 0.42
MAOA P21397 5/20 0.40
MAOB P27338 5/20 0.40
KDM1A O60341 4/20 0.40
CYP2C19 P33261 4/20 0.40
CYP2B6 P20813 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
AKR1C3 P42330 1/20 0.40
AKR1C1 Q04828 1/20 0.40
LMNA P02545 1/20 0.40
CYP3A4 P08684 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CYP2A6 P11509 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35975 0.83 SLC18A3 (0.45) SLC18A3SIGMAR1GAAMAPTCYP2C19
SCHEMBL29557767 0.83 SLC18A3 (0.45) SLC18A3SIGMAR1GAAMAPTCYP2C19
SCHEMBL2013478 0.82 SLC18A3 (0.48) SLC18A3SIGMAR1GAAMAPTTSHR
SCHEMBL10519427 0.79 SLC18A3 (0.42) SLC18A3SIGMAR1CYP2C19CYP2D6DRD3
SCHEMBL11796659 0.78 SLC18A3 (0.42) SLC18A3SIGMAR1TSHRCYP1A2CYP2D6
SCHEMBL11796662 0.78 SLC18A3 (0.42) SLC18A3SIGMAR1TSHRCYP1A2CYP2D6
Bicarbonate SCHEMBL11313316 0.76 AKR1C3 (0.46) SLC18A3SIGMAR1GAAMAPTAKR1C3
SCHEMBL11661537 0.75 SLC18A3 (0.52) SLC18A3SIGMAR1GAAMAPTTSHR
SCHEMBL41763 0.75
SCHEMBL2766491 0.75 SLC18A3 (0.52) SLC18A3SIGMAR1GAAMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5908692-A Ordered organic monolayers and methods of preparation thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1999-06-01 US claimed
US-20250388841-A1 WELL PLATE AND CULTURE METHOD MITSUI CHEMICALS, INC. (JP) 2025-12-25 US disclosed
US-12378218-B2 Cyclopentane compounds DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2025-08-05 US disclosed
WO-2024009636-A1 WELL PLATE AND CULTURE METHOD 三井化学株式会社 2024-01-11 WO disclosed
WO-2023091591-A1 POLYMER BLENDS HAVING IMPROVED ION CONDUCTIVITY, DEVICES, AND METHODS The Florida State University Research Foundation, Inc. (US) 2023-05-25 WO disclosed
CN-112424182-B Cyclopentane compounds 迪哲(江苏)医药股份有限公司 2023-05-23 CN disclosed
US-20230151211-A1 Polymer Blends Having Improved Ion Conductivity, Devices, and Methods NATIONAL SCIENCE FOUNDATION 2023-05-18 US disclosed
EP-3790870-B1 CYCLOPENTANE COMPOUNDS DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) 2023-04-19 EP disclosed
US-20220194922-A1 CYCLOPENTANE COMPOUNDS DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) 2022-06-23 US disclosed
US-11274091-B2 Cyclopentane compounds DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2022-03-15 US disclosed
EP-3790870-A1 CYCLOPENTANE COMPOUNDS DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD (CN) 2021-03-17 EP disclosed
US-10640587-B2 Polystyrene sulfonate analogs and methods FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2020-05-05 US disclosed
WO-2019215268-A1 CYCLOPENTANE COMPOUNDS ASTRAZENECA AB (SE) 2019-11-14 WO disclosed
US-20180265607-A1 Polystyrene Sulfonate Analogs and Methods FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2018-09-20 US disclosed
US-9243098-B2 Compound, polymer, cross-linked compound of polymer, and optical element including cross-linked compound CANON KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-20140163175-A1 NOVEL COMPOUND, POLYMER, CROSS-LINKED COMPOUND OF POLYMER, AND OPTICAL ELEMENT INCLUDING CROSS-LINKED COMPOUND CANON KABUSHIKI KAISHA (JP) 2014-06-12 US disclosed
WO-2013018817-A1 NOVEL COMPOUND, POLYMER, CROSS-LINKED COMPOUND OF POLYMER, AND OPTICAL ELEMENT INCLUDING CROSS-LINKED COMPOUND CANON KABUSHIKI KAISHA (JP) 2013-02-07 WO disclosed
US-5908692-A Ordered organic monolayers and methods of preparation thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1999-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378218-B2 Cyclopentane compounds CYP11B2, CYP11B1, SQLE SLC18A3 3688/4885SIGMAR1 2033/4885GAA 1157/4885
US-20220194922-A1 CYCLOPENTANE COMPOUNDS CYP11B2, CYP11B1, SQLE SLC18A3 3688/4885SIGMAR1 2033/4885GAA 1157/4885
US-11274091-B2 Cyclopentane compounds CYP11B2, CYP11B1, SQLE SLC18A3 3688/4885SIGMAR1 2033/4885GAA 1157/4885
US-20250388841-A1 WELL PLATE AND CULTURE METHOD LCP1, CD14, TLL2 SLC18A3 4728/4885SIGMAR1 1897/4885GAA 2286/4885
US-20140163175-A1 NOVEL COMPOUND, POLYMER, CROSS-LINKED COMPOUND OF POLYMER, AND OPTICAL ELEMENT INCLUDING CROSS-LINKED COMPOUND PCLAF, PCNA, SMC2 SLC18A3 4033/4885SIGMAR1 4399/4885GAA 3013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.