SCHEMBL8510778

SCHEMBL8510778

Oc1ccc2c3c(ccc2c1)C1(OCc2ccccc21)c1cc(Cl)c(O)cc1O3

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
SMAD3 P84022 1/20 0.32
KMT2A Q03164 1/20 0.32
PRMT1 Q99873 1/20 0.32
ACE2 Q9BYF1 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
DHFR P00374 1/20 0.31
TYMS P04818 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8509074 0.88 FTO (0.41) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL8508597 0.82 FTO (0.34) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL5266530 0.81 FTO (0.57) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL29365877 0.81 FTO (0.57) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL3794922 0.75 FTO (0.54) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL31110327 0.74 DHFR (0.39) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL8508926 0.73 MAPT (0.50) MEN1MAPTHTTKMT2ATDP1
SCHEMBL24401890 0.72 FTO (0.51) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL24401901 0.72 FTO (0.51) FTOMEN1MAPTHPGDCYP2C19
SCHEMBL10145499 0.71 MAPT (0.48) FTOMEN1MAPTHPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5882936-A MEASURING CARBON DIOXIDE AND AMMONIA BLOOD GASES; PURIFICATION; FORMING SENSOR COMPRISING MICROCOMPARTMENTS OF AQUEOUS BUFFER DISPERSED IN CROSSLINKED POLYMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-03-16 US disclosed
US-5822137-A Assembly for retaining optical components MINNESOTA MINING & MANUFACTURING CO. (US) 1998-10-13 US disclosed
US-5714122-A GAS SENSOR; DISPERSED FIRST PHASE CONTAINING INDICATOR WHICH PROVIDES SIGNAL IN RESPONSE TO CONCENTRATION OF GAS IN SAMPLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-02-03 US disclosed