Sugi Predict

Sugi Predict / Compounds / SCHEMBL5266530

SCHEMBL5266530

SCHEMBL5266530

O=C1OC2(c3cc(Cl)c(O)cc3Oc3c2ccc2cc(O)ccc32)c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 6/20 0.57
▸ MAPT P10636 4/20 0.57
▸ MEN1 O00255 4/20 0.57
▸ KMT2A Q03164 4/20 0.57
▸ TDP1 Q9NUW8 3/20 0.57
▸ HTT P42858 2/20 0.57
▸ RECQL P46063 2/20 0.57
▸ BLM P54132 2/20 0.57
▸ PRMT1 Q99873 2/20 0.57
▸ ACE2 Q9BYF1 2/20 0.57
▸ HPGD P15428 1/20 0.57
▸ CYP2C19 P33261 1/20 0.57
▸ SMAD3 P84022 1/20 0.57
▸ LMNA P02545 3/20 0.48
▸ GPR55 Q9Y2T6 2/20 0.48
▸ GNG2 P59768 1/20 0.48
▸ GNB1 P62873 1/20 0.48
▸ POLB P06746 1/20 0.48
▸ ALOX12 P18054 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365877 1.00 FTO (0.57) FTOMAPTMEN1KMT2ATDP1
SCHEMBL10005881 0.89 FTO (0.64) FTOMAPTMEN1KMT2ATDP1
SCHEMBL29362878 0.88 FTO (0.73) FTOMAPTMEN1KMT2ATDP1
SCHEMBL5270629 0.88 FTO (0.73) FTOMAPTMEN1KMT2ATDP1
SCHEMBL10145499 0.88 MAPT (0.48) FTOMAPTMEN1KMT2ATDP1
SCHEMBL31110329 0.86 FTO (0.65) FTOMAPTMEN1KMT2ATDP1
SCHEMBL2586810 0.86 MAPT (0.64) FTOMAPTMEN1KMT2ATDP1
SCHEMBL29376609 0.86 MAPT (0.64) FTOMAPTMEN1KMT2ATDP1
SCHEMBL4173117 0.85 FTO (0.79) FTOMAPTMEN1KMT2ATDP1
SCHEMBL29871701 0.85 FTO (0.79) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0731664-B1 SENSOR WITH IMPROVED DRIFT STABILITY TERUMO CARDIOVASCULAR SYS (US) 2002-02-27 — — EP claimed
US-5607645-A Sensor with improved drift stability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-04 — — US claimed
US-5498549-A A FLUORESCENT POLYNUCLEAR COMPOUND COVALENTLY BONDED TO A POLYSILOXANE MATRIX, BLOOD GASES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-03-12 — — US claimed
US-5403746-A Aqueous first phase comprising pH sensitive indicator in buffer solution dispersed in hydrophobic second phase permeable to analyte and impermeable to ionized hydrogen MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-04 — — US claimed
US-12042281-B2 Fluorescent nanomaterial sensors and related methods TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) 2024-07-23 — — US disclosed
US-20210015410-A1 FLUORESCENT NANOMATERIAL SENSORS AND RELATED METHODS TERUMO CARDIOVASCULAR SYSTEMS CORPORATION 2021-01-21 — — US disclosed
US-8114904-B2 Luminescence quenchers and fluorogenic probes for detection of reactive species Versitech Limited & Morningside Ventures Limited (CN) 2012-02-14 — — US disclosed
US-8114904-B2 Luminescence quenchers and fluorogenic probes for detection of reactive species Versitech Limited & Morningside Ventures Limited (CN) 2012-02-14 — — US disclosed
US-20090253118-A1 LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES VERSITECH LIMITED (CN) 2009-10-08 — — US disclosed
US-20090253118-A1 LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES VERSITECH LIMITED (CN) 2009-10-08 — — US disclosed
WO-2009121247-A1 LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES VERSITECH LIMITED (CN) 2009-10-08 — — WO disclosed
EP-0963567-B1 ASSEMBLY FOR RETAINING OPTICAL COMPONENTS TERUMO CARDIOVASCULAR SYS (US) 2007-10-10 — — EP disclosed
EP-0539968-B1 Exciplex-based sensors and methods for sensing MINNESOTA MINING & MFG (US) 1998-07-15 — — EP disclosed
WO-1997019348-A2 NOVEL EMULSION FOR ROBUST SENSING OF GASES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-05-29 — — WO disclosed
US-5607645-A Sensor with improved drift stability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-04 — — US disclosed
US-5498549-A A FLUORESCENT POLYNUCLEAR COMPOUND COVALENTLY BONDED TO A POLYSILOXANE MATRIX, BLOOD GASES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-03-12 — — US disclosed
US-5409666-A Quantitative analysis MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-25 — — US disclosed
US-5403746-A Aqueous first phase comprising pH sensitive indicator in buffer solution dispersed in hydrophobic second phase permeable to analyte and impermeable to ionized hydrogen MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-04 — — US disclosed
EP-0539968-A1 Exciplex-based sensors and methods for sensing MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-05 — — EP disclosed
US-4075064-A PRINTING, PLATING OTSU IWAO 1978-02-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253118-A1 LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES ROS1, LPO, HMOX1 FTO 244/4885MAPT 4349/4885MEN1 4478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.