SCHEMBL29365877

SCHEMBL29365877

O=C1OC2(c3cc(Cl)c(O)cc3Oc3c2ccc2cc(O)ccc32)c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 6/20 0.57
MAPT P10636 4/20 0.57
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
TDP1 Q9NUW8 3/20 0.57
HTT P42858 2/20 0.57
RECQL P46063 2/20 0.57
BLM P54132 2/20 0.57
PRMT1 Q99873 2/20 0.57
ACE2 Q9BYF1 2/20 0.57
HPGD P15428 1/20 0.57
CYP2C19 P33261 1/20 0.57
SMAD3 P84022 1/20 0.57
LMNA P02545 3/20 0.48
GPR55 Q9Y2T6 2/20 0.48
GNG2 P59768 1/20 0.48
GNB1 P62873 1/20 0.48
POLB P06746 1/20 0.48
ALOX12 P18054 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5266530 1.00 FTO (0.57) FTOMAPTMEN1KMT2ATDP1
SCHEMBL10005881 0.89 FTO (0.64) FTOMAPTMEN1KMT2ATDP1
SCHEMBL29362878 0.88 FTO (0.73) FTOMAPTMEN1KMT2ATDP1
SCHEMBL5270629 0.88 FTO (0.73) FTOMAPTMEN1KMT2ATDP1
SCHEMBL10145499 0.88 MAPT (0.48) FTOMAPTMEN1KMT2ATDP1
SCHEMBL31110329 0.86 FTO (0.65) FTOMAPTMEN1KMT2ATDP1
SCHEMBL2586810 0.86 MAPT (0.64) FTOMAPTMEN1KMT2ATDP1
SCHEMBL29376609 0.86 MAPT (0.64) FTOMAPTMEN1KMT2ATDP1
SCHEMBL4173117 0.85 FTO (0.79) FTOMAPTMEN1KMT2ATDP1
SCHEMBL29871701 0.85 FTO (0.79) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107198-A1 ANTIBODY BIOMARKER TO DIAGNOSE IDIOPATHIC INFLAMMATORY MYOPATHIES OHIO STATE INNOVATION FOUNDATION (US) 2026-05-21 WO disclosed
US-20260125675-A1 DOWNREGULATING TROLLS USING NOVEL ANTISENSE OLIGONUCLEOTIDES TO OVERCOME RESISTANCE TO CHEMOTHERAPY H LEE MOFFITT CANCER CENTER AND RESEARCH INST INC (US) 2026-05-07 US disclosed
EP-4731758-A2 ANTIGEN-SPECIFIC T CELL RECEPTORS AND CHIMERIC ANTIGEN RECEPTORS, AND METHODS OF USE IN IMMUNE SIGNALING MODULATION FOR CANCER IMMUNOTHERAPY The Methodist Hospital (US) 2026-04-29 EP disclosed
US-12590974-B2 Methods and compositions for cardiovascular disease detection and management OHIO STATE INNOVATION FOUNDATION (US) 2026-03-31 US disclosed
EP-4705328-A2 METHODS AND PLATFORM RELATED TO FLUORESCENT PROTEIN BIOSENSORS Board of Regents, The University of Texas System (US) 2026-03-11 EP disclosed
US-20260062756-A1 DIAGNOSTIC TO SUPPORT CLINICAL TRIAL MATCHING AND EXPLORATORY BIOMARKER ANALYSES IN CANCER PATIENTS H LEE MOFFITT CANCER CT & RES (US) 2026-03-05 US disclosed
US-12565680-B2 Cancer neoantigens and their utilities in cancer vaccines and TCR-based cancer immunotherapy THE METHODIST HOSPITAL SYSTEM (US) 2026-03-03 US disclosed
US-20260043086-A1 PREDICTIVE BIOMARKER IN AVASTIN IN COLON CANCER H LEE MOFFITT CANCER CT & RES (US) 2026-02-12 US disclosed
EP-4689667-A1 METHODS OF IDENTIFYING IMMUNOGLOBULIN ASSOCIATED WITH ADVERSE REACTIONS CSL Behring AG (CH) 2026-02-11 EP disclosed
US-20260021142-A1 HYDROGELS HAVING CONTROLLED HYDROLYTIC DEGRADATION GEORGIA TECH RES INST (US) 2026-01-22 US disclosed
EP-3990011-A1 A PEPTIDE-BASED SCREENING METHOD TO IDENTIFY NEOANTIGENS FOR USE WITH TUMOR INFILTRATING LYMPHOCYTES H. Lee Moffitt Cancer Center & Research Institute, Inc. (US) 2022-05-04 EP disclosed
EP-3986461-A1 METHODS AND COMPOSITION FOR A BINDING MOLECULE TARGETING CANCER CELLS EXPRESSING SSX2 PEPTIDE 41-49 IN HLA-A*0201 CONTEXT Children's National Medical Center (US) 2022-04-27 EP disclosed
EP-3980451-A1 ARTIFICIAL RECEPTORS, RECOMBINANT CELLS COMPRISING THEREOF, METHODS FOR THEIR PREPARATION, AND METHOD OF USING THEREOF Yeda Research and Development Co. Ltd (IL) 2022-04-13 EP disclosed
US-11287427-B2 Application of anti-CD39L3 antibodies for use in disease diagnostics and imaging VANDERBILT UNIVERSITY (US) 2022-03-29 US disclosed
US-20220064697-A1 AMPLIFICATION METHODS AND SYSTEMS FOR MERFISH AND OTHER APPLICATIONS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-03-03 US disclosed
US-11254786-B2 Multifunctional degradable nanoparticles with control over size and functionalities VANDERBILT UNIVERSITY (US) 2022-02-22 US disclosed
US-20220050096-A1 ANALYTE-SENSITIVE PROBES AND CONTACT LENS FOR DIAGNOSIS OF OCULAR PATHOLOGIES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-02-17 US disclosed
WO-2022032129-A1 SINGLE-CELL LOCUS-SPECIFIC PROFILING OF EPIGENETIC MARKS YALE UNIVERSITY (US) 2022-02-10 WO disclosed
WO-2021263211-A9 ANTIGEN-SPECIFIC T CELL RECEPTORS AND CHIMERIC ANTIGEN RECEPTORS, AND METHODS OF USE IN IMMUNE SIGNALING MODULATION FOR CANCER IMMUNOTHERAPY Houston Methodist Hospital (US) 2022-02-03 WO disclosed
CN-113994001-A Imaging-based hybrid CRISPR screening 哈佛学院院长及董事 2022-01-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11254786-B2 Multifunctional degradable nanoparticles with control over size and functionalities DSTN, PARN, CTSA FTO 865/4885MAPT 1922/4885MEN1 1242/4885
US-12590974-B2 Methods and compositions for cardiovascular disease detection and management TNNT2, SPTBN1, ATP2A2 FTO 4589/4885MAPT 1246/4885MEN1 2546/4885
US-20260021142-A1 HYDROGELS HAVING CONTROLLED HYDROLYTIC DEGRADATION KDM8, PTMS, USP2 FTO 462/4885MAPT 3125/4885MEN1 4461/4885
US-12565680-B2 Cancer neoantigens and their utilities in cancer vaccines and TCR-based cancer immunotherapy KDM2A, KDM1A, KDM3A FTO 428/4885MAPT 1531/4885MEN1 3376/4885
US-20260125675-A1 DOWNREGULATING TROLLS USING NOVEL ANTISENSE OLIGONUCLEOTIDES TO OVERCOME RESISTANCE TO CHEMOTHERAPY PDCD1LG2, TRMT1L, TTLL12 FTO 3621/4885MAPT 1637/4885MEN1 3567/4885
US-20260062756-A1 DIAGNOSTIC TO SUPPORT CLINICAL TRIAL MATCHING AND EXPLORATORY BIOMARKER ANALYSES IN CANCER PATIENTS CDK12, CHEK1, AURKB FTO 4523/4885MAPT 3960/4885MEN1 1530/4885
US-20260043086-A1 PREDICTIVE BIOMARKER IN AVASTIN IN COLON CANCER WEE2, PARP2, FLT4 FTO 4759/4885MAPT 4590/4885MEN1 1805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.