Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510866 | 0.86 | TDP1 (0.32) | TTRTDP1NPC1ALDH1A1LMNA | |
| SCHEMBL692167 | 0.83 | TTR (0.38) | CYP2D6TTRMYCTSHRSMN1; SMN2 | |
| SCHEMBL8960457 | 0.76 | TDP1 (0.37) | TTRTDP1MYCTSHRSMN1; SMN2 | |
| SCHEMBL11692937 | 0.74 | TSHR (0.45) | MYCALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL8960462 | 0.73 | TDP1 (0.37) | TDP1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8584862 | 0.72 | MYC (0.41) | CYP2D6TTRTDP1MYCNPC1 | |
| SCHEMBL8507974 | 0.72 | PTGS2 (0.36) | TDP1NPC1ALDH1A1LMNATP53 | |
| SCHEMBL11798381 | 0.71 | HSD11B1 (0.39) | MYCALDH1A1LMNAMAPTHTT | |
| SCHEMBL176809 | 0.71 | TTR (0.38) | TTRTDP1MYCALDH1A1LMNA | |
| SCHEMBL692394 | 0.70 | MYC (0.37) | CYP2D6TTRTDP1MYCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5980590-A | HIGH COLOR YIELD; FOR DYEING OR PRINTING OF CELLULOSIC FIBERS, WOOL, AND POLYAMIDE FIBERS | DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1999-11-09 | — | — | US | disclosed |