SCHEMBL8960462

SCHEMBL8960462

C=Cc1ccc[c]c1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8510866 0.76 TDP1 (0.32) TDP1ALDH1A1TSHRSMN1; SMN2
SCHEMBL11644363 0.74 GABRA1 (0.40) TDP1ALDH1A1
SCHEMBL8510865 0.73 CYP2D6 (0.34) TDP1ALDH1A1TSHRSMN1; SMN2
SCHEMBL483018 0.72 SMN1; SMN2 (0.34) TDP1ALDH1A1TSHRSMN1; SMN2
SCHEMBL692167 0.72 TTR (0.38) TSHRSMN1; SMN2
SCHEMBL691617 0.72 ALDH1A1 (0.35) TDP1ALDH1A1TSHRSMN1; SMN2
Vinylsulfonic Acid SCHEMBL28173703 0.71 TDP1 (0.45) TDP1ALDH1A1TSHRSMN1; SMN2
SCHEMBL696313 0.71 TSHR (0.33) ALDH1A1TSHRSMN1; SMN2
SCHEMBL458583 0.71 TTR (0.41) TDP1ALDH1A1TSHRSMN1; SMN2
Sulfuric Acid SCHEMBL968452 0.71 ALDH1A1 (0.48) TDP1ALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694588-A1 Triphendioxazine reactive dyes, preparation and use thereof BAYER AG (DE) 1996-01-31 EP disclosed