SCHEMBL8510909

SCHEMBL8510909

ClCCCC(CCCOCc1ccccc1)(CCCOCc1ccccc1)CCCOCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
NAAA Q02083 4/20 0.41
HRH4 Q9H3N8 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
LTA4H P09960 1/20 0.40
TEAD3 Q99594 1/20 0.39
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1001167 0.85 TSHR (0.58) TSHRL3MBTL1TDP1NAAAHRH4
SCHEMBL8998380 0.83 TSHR (0.56) TSHRL3MBTL1TDP1NAAAHRH4
SCHEMBL3488296 0.83 TSHR (0.56) TSHRL3MBTL1TDP1NAAAHRH4
SCHEMBL13399128 0.83 TSHR (0.47) TSHRL3MBTL1TDP1NAAAHRH4
SCHEMBL3289641 0.82 L3MBTL1 (0.54) TSHRL3MBTL1TDP1NAAAHRH4
SCHEMBL10826161 0.82 L3MBTL1 (0.54) TSHRL3MBTL1TDP1NAAAHRH4
SCHEMBL6941525 0.82 L3MBTL1 (0.54) TSHRL3MBTL1TDP1NAAAHRH4
SCHEMBL10825883 0.82 L3MBTL1 (0.54) TSHRL3MBTL1TDP1NAAAHRH4
SCHEMBL16359215 0.80 TSHR (0.44) TSHRL3MBTL1TDP1NAAAHRH4
SCHEMBL13399623 0.79 TEAD3 (0.45) TSHRL3MBTL1TEAD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9389227-B2 Solid substrate comprising array of dendrons and methods for using the same POSCO (KR) 2016-07-12 US disclosed
US-9389227-B2 Solid substrate comprising array of dendrons and methods for using the same POSCO (KR) 2016-07-12 US disclosed
US-9201067-B2 Size-controlled macromolecule POSCO (KR) 2015-12-01 US disclosed
US-9201067-B2 Size-controlled macromolecule POSCO (KR) 2015-12-01 US disclosed
US-9175335-B2 Biomolecule interaction using atomic force microscope POSCO (KR) 2015-11-03 US disclosed
US-20140315319-A1 BIOMOLECULE INTERACTION USING ATOMIC FORCE MICROSCOPE POSCO (KR) 2014-10-23 US disclosed
US-8673621-B2 Biomolecule interaction using atomic force microscope POSTECH FOUNDATION (KR) 2014-03-18 US disclosed
US-20100093553-A1 Solid Substrate Comprising Array of Dendrons and Methods for Using the Same PARK JOON WON 2010-04-15 US disclosed
US-20100093553-A1 Solid Substrate Comprising Array of Dendrons and Methods for Using the Same PARK JOON WON 2010-04-15 US disclosed
WO-2007135483-A2 BIOMOLECULE INTERACTION USING ATOMIC FORCE MICROSCOPE POHANG UNIVERSITY OF SCIENCE AND TECHNOLOGY (US) 2007-11-29 WO disclosed
EP-0722473-A4 METALLOSPHERES AND SUPERCLUSTERS UNIV SOUTH FLORIDA (US) 1999-10-06 EP disclosed
EP-0722473-A1 METALLOSPHERES AND SUPERCLUSTERS UNIVERSITY OF SOUTH FLORIDA (US) 1996-07-24 EP disclosed
WO-1995007315-A1 METALLOSPHERES AND SUPERCLUSTERS UNIVERSITY OF SOUTH FLORIDA (US) 1995-03-16 WO disclosed