Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 16/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216126 | 0.96 | SIGMAR1 (0.53) | SIGMAR1TBXAS1TBXA2R | |
| SCHEMBL4535241 | 0.87 | SIGMAR1 (0.47) | SIGMAR1TBXAS1TBXA2R | |
| SCHEMBL9092744 | 0.82 | SIGMAR1 (0.53) | SIGMAR1TBXAS1TBXA2R | |
| SCHEMBL7810685 | 0.80 | TBXAS1 (0.46) | SIGMAR1TBXAS1 | |
| SCHEMBL6897257 | 0.79 | SIGMAR1 (0.54) | SIGMAR1TBXAS1TBXA2R | |
| SCHEMBL9943787 | 0.79 | SIGMAR1 (0.53) | SIGMAR1TBXAS1TBXA2R | |
| SCHEMBL14127624 | 0.79 | SIGMAR1 (0.53) | SIGMAR1TBXAS1TBXA2R | |
| SCHEMBL7535000 | 0.78 | MTNR1A (0.47) | SIGMAR1TBXAS1 | |
| SCHEMBL5092012 | 0.78 | SIGMAR1 (0.51) | SIGMAR1TBXAS1TBXA2R | |
| SCHEMBL9882949 | 0.78 | SIGMAR1 (0.51) | SIGMAR1TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145352-B2 | Quaternary N-(halomethyl) ammonium salts as therapeutic agents | UNIVERSIDAD DE CALDAS (CO) | 2015-09-29 | — | — | US | disclosed |
| US-20140194640-A1 | QUATERNARY N-(HALOMETHYL) AMMONIUM SALTS AS THERAPEUTIC AGENTS | UNIVERSIDAD DE ANTIOQUIA (CO) | 2014-07-10 | — | — | US | disclosed |
| WO-2013179244-A2 | QUATERNARY N-(HALOMETHYL) AMMONIUM SALTS AS THERAPEUTIC AGENTS | UNIVERSIDAD DE CALDAS (CO) | 2013-12-05 | — | — | WO | disclosed |
| US-20130296346-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2013-11-07 | — | — | US | disclosed |
| US-20130296346-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2013-11-07 | — | — | US | disclosed |
| US-20130296346-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2013-11-07 | — | — | US | disclosed |
| EP-2642987-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | Faes Farma, S.A. (ES) | 2013-10-02 | — | — | EP | disclosed |
| CN-103313707-A | Application, synthesis method and pharmaceutical composition of diphenyl-amine derivative | FAES FARMA SA | 2013-09-18 | — | — | CN | disclosed |
| EP-2465498-A1 | Diphenyl-amine derivatives: uses, process of synthesis and pharmaceutical compositions | FAES FARMA, S.A. (ES) | 2012-06-20 | — | — | EP | disclosed |
| EP-2465498-A1 | Diphenyl-amine derivatives: uses, process of synthesis and pharmaceutical compositions | FAES FARMA, S.A. (ES) | 2012-06-20 | — | — | EP | disclosed |
| WO-2012069442-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012069442-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2012-05-31 | — | — | WO | disclosed |
| US-4514414-A | NEUROLEPTIC AGENTS | SMITHKLINE BECKMAN CORPORATION (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0066456-B1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND THEIR ESTERS | SMITHKLINE BECKMAN CORPORATION (US) | 1985-04-24 | — | — | EP | disclosed |
| US-4383999-A | GAMMA-AMINOBUTYRIC ACID SEDATIVES, ANALGESTICS, ANTIEPILEPTIC, MUSCULAR AND PSYCHOLOGICAL DISORDERS | SMITHKLINE BECKMAN CORPORATION (US) | 1983-05-17 | — | — | US | disclosed |
| EP-0066456-A1 | N-substituted azaheterocyclic carboxylic acids and their esters | SMITHKLINE BECKMAN CORPORATION (US) | 1982-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296346-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | CYP2D6, DDC, PAH | SIGMAR1 1329/4885TBXAS1 517/4885TBXA2R 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.