Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 2/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514026 | 0.92 | HTR3A (0.35) | LMNAMAPT | |
| SCHEMBL1816275 | 0.90 | KDM4E (0.36) | MEN1POLBKMT2AKDM4ENPSR1 | |
| SCHEMBL8514919 | 0.88 | PDE3B (0.31) | — | |
| SCHEMBL8514916 | 0.88 | PDE3B (0.31) | — | |
| SCHEMBL8509708 | 0.87 | CNR1 (0.35) | MEN1POLBKMT2APTPN1 | |
| SCHEMBL30125445 | 0.87 | CNR1 (0.35) | MEN1POLBKMT2APTPN1 | |
| SCHEMBL8511775 | 0.85 | PDK2 (0.39) | MEN1KMT2AKDM4ENPSR1LMNA | |
| SCHEMBL1813140 | 0.83 | PTPN1 (0.37) | MEN1POLBKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL1814761 | 0.82 | ALDH1A1 (0.36) | MEN1KMT2AKDM4ELMNATSHR | |
| SCHEMBL1816802 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2AKDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139552-B2 | Indeno-fused naphthopyrans having ethylenically unsaturated groups | TRANSITIONS OPTICAL, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| WO-2013090220-A1 | INDENO-FUSED NAPHTHOPYRANS HAVING ETHYLENICALLY UNSATURATED GROUPS | PPG INDUSTRIES, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| US-20120132870-A1 | Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups | TRANSITIONS OPTICAL INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120132870-A1 | Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups | ACR, INTS6, B3GNT2 | MEN1 3787/4885POLB 3275/4885KMT2A 4609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.