Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1816275 | 0.91 | KDM4E (0.36) | ALDH1A1HPGDDRD2DRD4HRH2 | |
| SCHEMBL1813140 | 0.90 | PTPN1 (0.37) | ALDH1A1DRD2DRD4HRH2HRH1 | |
| SCHEMBL1814761 | 0.89 | ALDH1A1 (0.36) | PDK2S1PR1ALDH1A1HPGDHIF1A | |
| SCHEMBL8512746 | 0.87 | HTT (0.36) | PDK2HTR7ALDH1A1HPGDHIF1A | |
| SCHEMBL30125488 | 0.87 | PDK2 (0.47) | PDK2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL8513816 | 0.87 | PDK2 (0.47) | PDK2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL8511374 | 0.85 | MEN1 (0.33) | ALDH1A1KDM4ELMNATSHRMEN1 | |
| SCHEMBL1816802 | 0.83 | ALDH1A1 (0.40) | S1PR1ALDH1A1HPGDDRD2DRD4 | |
| SCHEMBL1812200 | 0.81 | PDK2 (0.48) | PDK2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL164608 | 0.81 | TSHR (0.41) | ALDH1A1HPGDDRD2DRD4HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139552-B2 | Indeno-fused naphthopyrans having ethylenically unsaturated groups | TRANSITIONS OPTICAL, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| WO-2013090220-A1 | INDENO-FUSED NAPHTHOPYRANS HAVING ETHYLENICALLY UNSATURATED GROUPS | PPG INDUSTRIES, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| US-20120132870-A1 | Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups | TRANSITIONS OPTICAL INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120132870-A1 | Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups | ACR, INTS6, B3GNT2 | PDK2 2446/4885HTR7 762/4885S1PR1 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.