Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609928 | 0.79 | HPGD (0.65) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL11321145 | 0.78 | HPGD (0.41) | ALDH1A1LMNAGAAKMT2AKDM4E | |
| SCHEMBL11307887 | 0.78 | NPC1 (0.46) | NPC1RAB9AALDH1A1LMNAGAA | |
| SCHEMBL10894670 | 0.77 | HDAC3 (0.57) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL8485409 | 0.76 | ALDH1A1 (0.63) | NPC1RAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL9353063 | 0.75 | EPHX2 (0.59) | MAPK1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL11309845 | 0.75 | MEN1 (0.46) | HDAC1HDAC8HDAC6ALDH1A1LMNA | |
| SCHEMBL1726043 | 0.73 | RAB9A (0.57) | NPC1RAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL11799525 | 0.73 | HDAC3 (0.53) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL11306216 | 0.73 | ALDH1A1 (0.47) | ALDH1A1GAAKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981491-A | PEPTIDES; METALLOENZYMES; TUMOR NECROSIS FACTOR | DARWIN DISCOVERY LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |