SCHEMBL8512336

SCHEMBL8512336

C=C(C)C(=O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.42
HSD11B1 P28845 5/20 0.41
GLA P06280 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
EPHX1 P07099 2/20 0.39
ALDH1A1 P00352 3/20 0.38
MAPT P10636 1/20 0.38
POLB P06746 1/20 0.38
CRHBP P24387 1/20 0.37
HTT P42858 1/20 0.37
CRHR2 Q13324 1/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
TSHR P16473 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2059655 0.83 EPHX1 (0.36) CA2HSD11B1GLAL3MBTL1EPHX1
SCHEMBL587576 0.81 HSD11B1 (0.49) HSD11B1L3MBTL1ALDH1A1TSHR
Methacrylic Acid SCHEMBL11899769 0.78 ALDH1A1 (0.44) CA2HSD11B1GLAL3MBTL1EPHX1
SCHEMBL28891341 0.77 HSD11B1 (0.41) CA2HSD11B1GLAL3MBTL1EPHX1
SCHEMBL10323133 0.77 GLA (0.41) HSD11B1GLAL3MBTL1EPHX1ALDH1A1
SCHEMBL19757635 0.75 HSD11B1 (0.47) CA2HSD11B1GLAL3MBTL1EPHX1
SCHEMBL6451090 0.75 ALDH1A1 (0.39) CA2HSD11B1GLAL3MBTL1EPHX1
SCHEMBL159994 0.75 HSD11B1 (0.47) CA2HSD11B1GLAL3MBTL1EPHX1
Methacrylic Acid SCHEMBL11899770 0.75 ALDH1A1 (0.38) CA2HSD11B1GLAL3MBTL1EPHX1
SCHEMBL14917397 0.75 TDP1 (0.46) HSD11B1GLAL3MBTL1EPHX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785100-B2 Two-component developer KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2014-07-22 US claimed
US-20130189612-A1 TWO-COMPONENT DEVELOPER KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-07-25 US claimed
US-12037679-B2 Method of forming a diamond film APPLIED MATERIALS, INC. (US) 2024-07-16 US disclosed
US-20230279540-A1 METHOD OF FORMING A DIAMOND FILM APPLIED MATERIALS, INC. (US) 2023-09-07 US disclosed
US-8785100-B2 Two-component developer KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2014-07-22 US disclosed
US-20130189612-A1 TWO-COMPONENT DEVELOPER KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-07-25 US disclosed
US-8389594-B2 Silicone-modified adamantane derivative, photo-radically curable resin composition, and method for preparing photo-radically curable resin composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-03-05 US disclosed
US-20120136086-A1 SILICONE-MODIFIED ADAMANTANE DERIVATIVE, PHOTO-RADICALLY CURABLE RESIN COMPOSITION, AND METHOD FOR PREPARING PHOTO-RADICALLY CURABLE RESIN COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136086-A1 SILICONE-MODIFIED ADAMANTANE DERIVATIVE, PHOTO-RADICALLY CURABLE RESIN COMPOSITION, AND METHOD FOR PREPARING PHOTO-RADICALLY CURABLE RESIN COMPOSITION RAD51, PRMT1, ARGLU1 CA2 4219/4885HSD11B1 3441/4885GLA 1159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.