Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9608614 | 0.91 | GPR52 (0.53) | GPR52FAAHTDP1L3MBTL1TBXAS1 | |
| SCHEMBL9608866 | 0.84 | MAPT (0.51) | GPR52MAPT | |
| SCHEMBL8512649 | 0.81 | GPR52 (0.57) | GPR52TBXAS1PTAFRCHRNA7 | |
| SCHEMBL8512647 | 0.81 | GPR52 (0.57) | GPR52TBXAS1PTAFRCHRNA7 | |
| SCHEMBL1404371 | 0.78 | FAAH (0.64) | FAAHTDP1L3MBTL1TBXAS1PTAFR | |
| SCHEMBL1404372 | 0.78 | FAAH (0.64) | FAAHTDP1L3MBTL1TBXAS1PTAFR | |
| SCHEMBL9608613 | 0.76 | MAPT (0.56) | GPR52MAPT | |
| SCHEMBL5962606 | 0.76 | RAB9A (0.53) | TDP1L3MBTL1KMT2AMAPTPOLB | |
| SCHEMBL5962608 | 0.76 | RAB9A (0.53) | TDP1L3MBTL1KMT2AMAPTPOLB | |
| SCHEMBL8514456 | 0.75 | CHRNA7 (0.49) | GPR52TDP1L3MBTL1TBXAS1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |