Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459926 | 0.84 | ALDH1A1 (0.40) | SMN1; SMN2LMNAMAPK1ALDH1A1RAB9A | |
| SCHEMBL8515784 | 0.81 | HPGD (0.43) | SMN1; SMN2LMNAMAPK1ALDH1A1MAPT | |
| SCHEMBL4560875 | 0.79 | CES1 (0.45) | SMN1; SMN2LMNAMAPK1ALDH1A1RAB9A | |
| SCHEMBL731382 | 0.79 | LMNA (0.43) | SMN1; SMN2LMNAMAPK1ALDH1A1MAPT | |
| SCHEMBL28392028 | 0.72 | TDP1 (0.76) | SMN1; SMN2LMNAMAPK1ALDH1A1RAB9A | |
| SCHEMBL9960489 | 0.72 | TDP1 (0.70) | SMN1; SMN2LMNAMAPK1RAB9AMAPT | |
| Benzoic Acid SCHEMBL2914560 | 0.72 | TSHR (0.48) | SMN1; SMN2LMNAMAPK1ALDH1A1HPGD | |
| Benzoic Acid SCHEMBL3384089 | 0.72 | DAO (0.58) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| Benzoic Acid SCHEMBL1969718 | 0.72 | DAO (0.58) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| Benzoic Acid SCHEMBL12981029 | 0.71 | TP53 (0.61) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069647-A1 | NOVEL 1H- SPIRO [NAPHTALENE- 2, 2 ' -OXIRANE] DERIVATIVES | GIVAUDAN SA (CH) | 2012-05-31 | — | — | WO | claimed |
| WO-2012070596-A1 | ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-05-31 | — | — | WO | disclosed |