Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.66 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.66 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.63 |
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851730 | 0.91 | FFAR1 (0.60) | MEN1KMT2AFFAR1FFAR4ALKBH1 | |
| SCHEMBL25203039 | 0.90 | NR4A2 (0.71) | FFAR1FFAR4ALKBH1MRGPRX4NR4A2 | |
| SCHEMBL30391969 | 0.90 | NR4A2 (0.71) | FFAR1FFAR4ALKBH1MRGPRX4NR4A2 | |
| SCHEMBL4684657 | 0.86 | NR4A2 (0.69) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL4266677 | 0.84 | FFAR1 (0.54) | MEN1KMT2AFFAR1FFAR4ALKBH1 | |
| SCHEMBL852236 | 0.84 | MEN1 (0.69) | MEN1KMT2AALKBH1MRGPRX4NR4A2 | |
| SCHEMBL28587004 | 0.83 | ALKBH1 (0.64) | FFAR1FFAR4ALKBH1MRGPRX4NR4A2 | |
| SCHEMBL1248693 | 0.83 | MAOB (0.66) | FFAR1FFAR4ALKBH1MRGPRX4MAOB | |
| SCHEMBL4684138 | 0.83 | MRGPRX4 (0.70) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL1426961 | 0.81 | MEN1 (1.00) | MEN1KMT2AMRGPRX4NR4A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2014-07-17 | — | — | US | disclosed |
| US-8722930-B2 | Protease inhibitors | ORION CORPORATION (FI) | 2014-05-13 | — | — | US | disclosed |
| US-20120136002-A1 | PROTEASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-31 | — | — | US | disclosed |
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | MEN1 258/4885KMT2A 3122/4885FFAR1 3640/4885 |
| US-20120136002-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | MEN1 258/4885KMT2A 3122/4885FFAR1 3640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.